ArticleJournal of bacteriology2006
Flavonoid-inducible modifications to rhamnan O antigens are necessary for Rhizobium sp. strain NGR234-legume symbioses.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 55 citations in OpenAlex.
- The Rhizobium-Legume Symbiosis: Co-opting Successful Stress Management.Frontiers in plant science · 2021Review
- Article
- Biofilm plasmids with a rhamnose operon are widely distributed determinants of the 'swim-or-stick' lifestyle in roseobacters.The ISME journal · 2016Article
- AFrontiers in cellular and infection microbiology · 2016Article
- Secretion systems and signal exchange between nitrogen-fixing rhizobia and legumes.Frontiers in plant science · 2015Review
- Lipopolysaccharides in diazotrophic bacteria.Frontiers in cellular and infection microbiology · 2014Review
- Fast induction of biosynthetic polysaccharide genes lpxA, lpxE, and rkpI of Rhizobium sp. strain PRF 81 by common bean seed exudates is indicative of a key role in symbiosis.Functional & integrative genomics · 2013Article
- Article
- Identifying abnormalities in symbiotic development between Trifolium spp. and Rhizobium leguminosarum bv. trifolii leading to sub-optimal and ineffective nodule phenotypes.Annals of botany · 2012Article
- Article
- Role of BacA in lipopolysaccharide synthesis, peptide transport, and nodulation by Rhizobium sp. strain NGR234.Journal of bacteriology · 2011Article
- Naringenin regulates expression of genes involved in cell wall synthesis in Herbaspirillum seropedicae.Applied and environmental microbiology · 2011Article
- Genetic basis for Rhizobium etli CE3 O-antigen O-methylated residues that vary according to growth conditions.Journal of bacteriology · 2010Article
- Symbiotic use of pathogenic strategies: rhizobial protein secretion systems.Nature reviews. Microbiology · 2009Review
- TtsI regulates symbiotic genes in Rhizobium species NGR234 by binding to tts boxes.Molecular microbiology · 2008Article
- Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius.PloS one · 2008Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizobium sp. strain NGR234 produces a flavonoid-inducible rhamnose-rich lipopolysaccharide (LPS) that is important for the nodulation of legumes. Many of the genes encoding the rhamnan part of the molecule lie between 87 degrees and 110 degrees of pNGR234a, the symbiotic plasmid of NGR234. Computational methods suggest that 5 of the 12 open reading frames (ORFs) within this arc are involved in synthesis (and subsequent polymerization) of L-rhamnose. Two others probably play roles in the transport of carbohydrates. To evaluate the function of these ORFs, we mutated a number of them and tested the ability of the mutants to nodulate a variety of legumes. At the same time, changes in the production of surface polysaccharides (particularly the rhamnan O antigen) were examined. Deletion of rmlB to wbgA and mutation in fixF abolished rhamnan synthesis. Mutation of y4gM (a member of the ATP-binding cassette transporter family) did not abolish production of the rhamnose-rich LPS but, unexpectedly, the mutant displayed a symbiotic phenotype very similar to that of strains unable to produce the rhamnan O antigen (NGRDeltarmlB-wbgA and NGROmegafixF). At least two flavonoid-inducible regulatory pathways are involved in synthesis of the rhamnan O antigen. Mutation of either pathway reduces rhamnan production. Coordination of rhamnan synthesis with rhizobial release from infection threads is thus part of the symbiotic interaction.
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