Evidence map›Paper›PMID 16672431›Full record

ArticleJournal of clinical microbiology2006

PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis.

Ramadass Balamurugan, Subramanian Venkataraman, K R John, Balakrishnan S Ramakrishna

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The diagnostic value of polymerase chain reaction forSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Inflammatory bowel disease: An Indian perspective.The Indian journal of medical research · 2021
    Review
  8. Review
  9. A new diagnostic tool for rapid and accurate detection ofSaudi journal of biological sciences · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A 39-year-old female immigrant with chronic diarrhea.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2014
    Article
  15. Article
  16. Fluorescent quantitative PCR of Mycobacterium tuberculosis for differentiating intestinal tuberculosis from Crohn's disease.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ramadass BalamuruganDepartment of Gastrointestinal Sciences, Christian Medical College, Ida Scudder Road, Vellore 632004, Tamil Nadu, India.
Subramanian Venkataraman
K R John
Balakrishnan S Ramakrishna
Christian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis in fecal samples was evaluated in the diagnosis of intestinal tuberculosis (ITB). The numbers of samples that tested positive by PCR with SalI digestion were 16/18 untreated-ITB samples, 0/8 treated-ITB samples, 12/14 smear-positive pulmonary tuberculosis samples, and 0/30 control samples. The sensitivity, specificity, positive predictive value, and negative predictive value of fecal PCR were 88.8%, 100%, 100%, and 93.7%, respectively.

Indexed as

Base SequenceCase-Control StudiesDNA, BacterialDNA Transposable ElementsFecesHumansMycobacterium tuberculosisPolymerase Chain ReactionPredictive Value of TestsSensitivity and SpecificityTuberculosis, GastrointestinalTuberculosis, PulmonaryDNA, BacterialDNA Transposable Elements

Identifiers

PMID16672431
PMCPMC1479206
OpenAlexW2139971291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.