Evidence map›Paper›PMID 16672429›Full record

ArticleJournal of clinical microbiology2006

Plasma and liver hepatitis C virus variability in patients coinfected with human immunodeficiency virus.

Anne-Christine Jouvencel, Didier Neau, Muriel Faure, Martine Neau, Christophe Martinaud, Elisabeth Legrand, Pascale Trimoulet, Isabelle Garrigue, Brigitte Le Bail, Paulette Bioulac-Sage and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Anne-Christine JouvencelLaboratoire de Virologie EA2968, Universite Victor Segalen Bordeaux 2, 146 Rue Léo Saignat, 33076 Bordeaux, France.
Didier Neau
Muriel Faure
Martine Neau
Christophe Martinaud
Elisabeth Legrand
Pascale Trimoulet
Isabelle Garrigue
Brigitte Le Bail
Paulette Bioulac-Sage
Michel Dupon
Jean-Marie Ragnaud
Herve Fleury
Marie-Edith Lafon
Centre Hospitalier Universitaire de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver and plasma hepatitis C virus (HCV) variability was compared by E2 cloning and sequencing in three patients coinfected with HCV and human immunodeficiency virus (HIV) before and after interferon treatment and in three patients solely infected with HCV. The plasma and liver samples contained unique sequences. In the patients coinfected with HIV, accumulated random mutations produced mostly nonsynonymous substitutions in contrast to the reduced HCV genetic variability seen after treatment.

Indexed as

Case-Control StudiesGenetic VariationGenotypeHepacivirusHepatitis CHIV InfectionsHumansInterferonsLiverOrgan SpecificityViremiaInterferons

Identifiers

PMID16672429
PMCPMC1479191
OpenAlexW2153765084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.