ArticleProceedings of the National Academy of Sciences of the United States of America2006
The sulfur acclimation SAC3 kinase is required for chloroplast transcriptional repression under sulfur limitation in Chlamydomonas reinhardtii.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Nitric Oxide Remodels the Photosynthetic Apparatus upon S-Starvation inPlant physiology · 2019Article
- Transcriptome profiling of sulfate deprivation responses in two agarophytes Gracilaria changii and Gracilaria salicornia (Rhodophyta).Scientific reports · 2017Article
- Article
- Deletion of Proton Gradient Regulation 5 (PGR5) and PGR5-Like 1 (PGRL1) proteins promote sustainable light-driven hydrogen production in Chlamydomonas reinhardtii due to increased PSII activity under sulfur deprivation.Frontiers in plant science · 2015Article
- Critical function of a Chlamydomonas reinhardtii putative polyphosphate polymerase subunit during nutrient deprivation.The Plant cell · 2014Article
- De novo transcriptomic analysis of hydrogen production in the green alga Chlamydomonas moewusii through RNA-Seq.Biotechnology for biofuels · 2013Article
- Tiered regulation of sulfur deprivation responses in Chlamydomonas reinhardtii and identification of an associated regulatory factor.Plant physiology · 2013Article
- Circadian regulation of chloroplast transcription in Chlamydomonas is accompanied by little or no fluctuation in RPOD levels or core RNAP activity.Molecular biology reports · 2012Article
- SNF1-related protein kinases type 2 are involved in plant responses to cadmium stress.Plant physiology · 2012Article
- Hydrogen photo-evolution upon S deprivation stepwise: an illustration of microalgal photosynthetic and metabolic flexibility and a step stone for future biotechnological methods of renewable H(2) production.Photosynthesis research · 2010Review
- RNA-seq analysis of sulfur-deprived Chlamydomonas cells reveals aspects of acclimation critical for cell survival.The Plant cell · 2010Article
- Genetic interactions between regulators of Chlamydomonas phosphorus and sulfur deprivation responses.Genetics · 2009Article
- The central role of a SNRK2 kinase in sulfur deprivation responses.Plant physiology · 2008Article
- Integration of chloroplast nucleic acid metabolism into the phosphate deprivation response in Chlamydomonas reinhardtii.The Plant cell · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulfur (S) deprivation responses have been studied extensively in algae and land plants; however, little is known of the signals that link perception of S status to chloroplast gene expression. Here, we have compared the chloroplast S limitation response in WT vs. sac1 and sac3 sulfur acclimation mutants of the green alga Chlamydomonas reinhardtii. We provide evidence that in the WT, chloroplast transcriptional activity rapidly decreases after removal of S from the medium, leading to reduced transcript accumulation. This decrease correlates with reduced abundance of a sigma70-like factor, Sig1, which is most likely the unique chloroplast transcription specificity factor. We further show that reduced transcription activity and diminished Sig1 accumulation are mediated by the SAC3 gene product, a putative Snf1-type Ser/Thr kinase previously shown to have both positive and negative effects on nuclear gene expression. Inclusion of the protein kinase inhibitor 6-dimethylaminopurine during S limitation yielded a pattern of expression that was largely similar to that seen in the sac3 mutant, lending support to the hypothesis that Sac3 kinase activation leads to transcriptional repression and Sig1 proteolysis. The finding that Sac3 regulates chloroplast gene expression suggests that it has a previously unknown role in integrating the S limitation response in multiple subcellular compartments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.