Evidence map›Paper›PMID 16672108›Full record

ArticleEpidemiology and infection2006

Risk factors for encephalitis and death from West Nile virus infection.

K Murray, S Baraniuk, M Resnick, R Arafat, C Kilborn, K Cain, R Shallenberger, T L York, D Martinez, J S Hellums and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 5 pooled it
10.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 5 syntheses or guidelines pooled it, 191 citations in OpenAlex.

  1. Pooled it
  2. Neuroinvasive West Nile virus infections after solid organ transplantation: Single center experience and systematic review.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
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  6. Trial
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Human antibodies against West Nile and related orthoflaviviruses.bioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

K MurrayUniversity of Texas, School of Public Health, Houston, TX, USA. Kristy.O.Murray@uth.tmc.edu
S Baraniuk
M Resnick
R Arafat
C Kilborn
K Cain
R Shallenberger
T L York
D Martinez
J S Hellums
D Hellums
M Malkoff
N Elgawley
W McNeely
S A Khuwaja
R B Tesh
Houston Health and Human Services Department · USThe University of Texas Health Science Center at Houston · USHarris Health System · USThe University of Texas at Austin · USThe University of Texas Medical Branch at Galveston · USADS Environmental Services (Malaysia)Baylor College of Medicine · US

Funding

Epidemiology of Arboviral Encephalomyelitis in HoustonK23AI057341 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MURRAY, KRISTY · 2005 to 2007
$363k
U.S. Based Collaboration in Emerging Viral and Prion Diseases-26625489N01AI025489 · NIAID · University of Texas Medical Branch · 2004 to 2004
–
NIAID NIH HHS K23 AI057341NIAID NIH HHS N01 AI025489NIAID NIH HHS N01-AI25489
6 · The paper itself

Abstract

We conducted a nested case-control study to determine potential risk factors for developing encephalitis from West Nile virus (WNV) infection. Retrospective medical chart reviews were completed for 172 confirmed WNV cases hospitalized in Houston between 2002 and 2004. Of these cases, 113 had encephalitis, including 17 deaths, 47 had meningitis, and 12 were fever cases; 67% were male. Homeless patients were more likely to be hospitalized from WNV compared to the general population. A multiple logistic regression model identified age [odds ratio (OR) 1.1, P<0.001], history of hypertension, including those cases taking hypertension-inducing drugs (OR 2.9, P=0.012), and history of cardiovascular disease (OR 3.5, P=0.061) as independent risk factors for developing encephalitis from WNV infection. After adjusting for age, race/ethnicity (being black) (OR 12.0, P<0.001), chronic renal disease (OR 10.6, P<0.001), hepatitis C virus (OR 23.1, P=0.0013), and immunosuppression (OR 3.9, P=0.033) were identified as risk factors for death from WNV infection.

Indexed as

AdolescentAdultAgedCase-Control StudiesChildChild, PreschoolEncephalitisFemaleHumansIll-Housed PersonsMaleMiddle AgedRetrospective StudiesRisk FactorsWest Nile Fever

Identifiers

PMID16672108
PMCPMC2870518
OpenAlexW2042771862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.