ArticleThorax2006
Utility of signs and symptoms of chronic cough in predicting specific cause in children.
Article in Thorax, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical pathways for chronic cough in children.The Cochrane database of systematic reviews · 2014Pooled it
- Trial
- Trial
- Expert opinion and clinical practice recommendations using a modified Delphi approach for pediatric acute cough evaluation and management in India.Lung India : official organ of Indian Chest Society · 2026Article
- A multi-disciplinary approach to chronic cough in children.Laryngoscope investigative otolaryngology · 2022Review
- History Taking as a Diagnostic Tool in Children With Chronic Cough.Frontiers in pediatrics · 2022Review
- Approach to chronic cough in children.Singapore medical journal · 2021Article
- Flexible Bronchoscopy in Evaluation of Persistent Wheezing in Children-Experiences from National Pediatric Center.Medicina (Kaunas, Lithuania) · 2020Article
- When the Cough Does Not Improve: A Review on Protracted Bacterial Bronchitis in Children.Frontiers in pediatrics · 2020Review
- 'Dry' and 'wet' cough: how reliable is parental reporting?BMJ open respiratory research · 2019Article
- ERS statement on protracted bacterial bronchitis in children.The European respiratory journal · 2017Review
- Article
- Prolonged Cough in Pediatric Population First Line Care, Belgian Guidelines.The open respiratory medicine journal · 2017Article
- Analysis of the Literature on Chronic Cough in Children.The open respiratory medicine journal · 2017Review
- Chronic suppurative lung disease in adults.Journal of thoracic disease · 2016Article
- Feed-forward and reciprocal inhibition for gain and phase timing control in a computational model of repetitive cough.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Article
- Protracted bacterial bronchitis: The last decade and the road ahead.Pediatric pulmonology · 2016Review
- Clinical characteristics of protracted bacterial bronchitis in Chinese infants.Scientific reports · 2015Article
- Article
- Epidemiology of tuberculosis in young children in the United States.Pediatrics · 2014Observational
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPaediatricians rely on cough descriptors to direct them to the level of investigations needed for a child presenting with chronic cough, yet there is a lack of published data to support this approach. A study was undertaken to evaluate (1) whether historical cough pointers can predict which children have a specific cause for their cough and (2) the usefulness of chest radiography and spirometry as standard investigations in children with chronic cough.
methodsThis was a prospective cohort study of children referred to a tertiary hospital with a cough lasting >3 weeks between June 2002 and July 2004. All included children completed a detailed history and examination using a standardised data collection sheet and followed a pathway of investigation until a diagnosis was made.
resultsIn 100 consecutively recruited children of median age 2.8 years, the best predictor of specific cough observed was a moist cough at the time of consultation with an odds ratio (OR) of 9.34 (95% CI 3.49 to 25.03). Chest examination or chest radiographic abnormalities were also predictive with OR 3.60 (95% CI 1.31 to 9.90) and 3.16 (95% CI 1.32 to 7.62), respectively. The most significant historical pointer for predicting a specific cause of the cough was a parental history of moist cough (sensitivity 96%, specificity 26%, positive predictive value 74%).
conclusionsThe most useful clinical marker in predicting specific cough is the presence of a daily moist cough. Both chest examination and chest radiographic abnormalities are also useful in predicting whether children have a specific cause of their cough.
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