Evidence map›Paper›PMID 16669784›Full record

ReviewAnnual review of plant biology2006

Phytochrome structure and signaling mechanisms.

Nathan C Rockwell, Yi-Shin Su, J Clark Lagarias

Abstract readReview
In one paragraph

Review in Annual review of plant biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 482 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
482citing papers in PubMed, 1 pooled it
57.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

482 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,088 citations in OpenAlex.

  1. Pooled it
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  12. Article
  13. Identification and Characterization of a Red-Light Sensor FphA inInternational journal of molecular sciences · 2026
    Article
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422 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nathan C RockwellSection of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.
Yi-Shin Su
J Clark Lagarias
University of California, Davis · US

Funding

MOLECULAR MECHANISMS OF PHYTOCHROME SIGNALINGR01GM068552 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI LAGARIAS, JOHN CLARK · 2003 to 2020
$5.3M
NIGMS NIH HHS GM068552NIGMS NIH HHS R01 GM068552
6 · The paper itself

Abstract

Phytochromes are a widespread family of red/far-red responsive photoreceptors first discovered in plants, where they constitute one of the three main classes of photomorphogenesis regulators. All phytochromes utilize covalently attached bilin chromophores that enable photoconversion between red-absorbing (P(r)) and far-red-absorbing (P(fr)) forms. Phytochromes are thus photoswitchable photosensors; canonical phytochromes have a conserved N-terminal photosensory core and a C-terminal regulatory region, which typically includes a histidine-kinase-related domain. The discovery of new bacterial and cyanobacterial members of the phytochrome family within the last decade has greatly aided biochemical and structural characterization of this family, with the first crystal structure of a bacteriophytochrome photosensory core appearing in 2005. This structure and other recent biochemical studies have provided exciting new insights into the structure of phytochrome, the photoconversion process that is central to light sensing, and the mechanism of signal transfer by this important family of photoreceptors.

Indexed as

Signal TransductionModels, MolecularPhytochromeProtein ConformationPhytochrome

Identifiers

PMID16669784
PMCPMC2664748
OpenAlexW2130662176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.