ArticleBritish journal of pharmacology1991
Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345.
Article in British journal of pharmacology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 220 citations in OpenAlex.
- Ion Channels Involved in Substance P-Mediated Nociception and Antinociception.International journal of molecular sciences · 2019Review
- Anxiolytic-like effects of the neurokinin 1 receptor antagonist GR-205171 in the elevated plus maze and contextual fear-potentiated startle model of anxiety in gerbils.Behavioural pharmacology · 2009Article
- The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.Psychopharmacology · 2007Article
- [3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain.British journal of pharmacology · 2006Article
- Chronic psychosocial stress in tree shrews: effect of the substance P (NK1 receptor) antagonist L-760735 and clomipramine on endocrine and behavioral parameters.Psychopharmacology · 2005Article
- Examining SLV-323, a novel NK1 receptor antagonist, in a chronic psychosocial stress model for depression.Psychopharmacology · 2005Article
- Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Inhibition of Ca(2+)-sensitive K+ currents in NG 108-15 cells by substance P and related tachykinins.British journal of pharmacology · 1996Article
- Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 1996Article
- The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture.Naunyn-Schmiedeberg's archives of pharmacology · 1996Article
- An isobolographic analysis of the effects of N-methyl-D-aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat.British journal of pharmacology · 1996Article
- The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist.British journal of pharmacology · 1995Article
- Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea-pig.British journal of pharmacology · 1995Article
- Antinociceptive activity of the tachykinin NK1 receptor antagonist, CP-99,994, in conscious gerbils.British journal of pharmacology · 1995Article
- Innervation of the synovium.Annals of the rheumatic diseases · 1995Review
- Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B.British journal of pharmacology · 1995Article
- Effects of RP 67580, a tachykinin NK1 receptor antagonist, on a primary afferent-evoked response of ventral roots in the neonatal rat spinal cord.British journal of pharmacology · 1994Article
- Differences in the distribution and characteristics of tachykinin NK1 binding sites between human and guinea pig lung.British journal of pharmacology · 1994Article
- Pharmacological characterisation of NK1 receptor antagonist, [D-Trp7]sendide, on behaviour elicited by substance P in the mouse.Naunyn-Schmiedeberg's archives of pharmacology · 1994Article
- Effect of the tachykinin NK1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cord.British journal of pharmacology · 1994Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The affinity of the non-peptide antagonist CP-96,345 for tachykinin NK1 receptors has been estimated in a range of species by use of both radioligand binding and functional assays. CP-96,345 was 30-120 fold less active at NK1 receptors in rat and mouse than in the other species examined, including man. These results demonstrate the existence of species variations in NK1 receptors.
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