ArticleGenes & development2006
Dynamic regulatory interactions of Polycomb group genes: MEDEA autoregulation is required for imprinted gene expression in Arabidopsis.
Article in Genes & development, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 146 citations in OpenAlex.
- United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals.The Journal of heredity · 2024Review
- Conserved noncoding sequences and de novo Mutator insertion alleles are imprinted in maize.Plant physiology · 2023Article
- Abscisic acid negatively regulates the Polycomb-mediated H3K27me3 through the PHD-finger protein, VIL1.The New phytologist · 2022Article
- The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis.Developmental cell · 2021Article
- Mutation of the imprinted gene OsEMF2a induces autonomous endosperm development and delayed cellularization in rice.The Plant cell · 2021Article
- SDG711 Is Involved in Rice Seed Development through Regulation of Starch Metabolism Gene Expression in Coordination with Other Histone Modifications.Rice (New York, N.Y.) · 2021Article
- Article
- Epigenetics Regulates Reproductive Development in Plants.Plants (Basel, Switzerland) · 2019Review
- Detailed observation on expression dynamics of Polycomb group genes during rice early endosperm development in subspecies hybridization reveals their characteristics of parent-of-origin genes.Rice (New York, N.Y.) · 2019Article
- Characterization of Imprinted Genes in Rice Reveals Conservation of Regulation and Imprinting with Other Plant Species.Plant physiology · 2018Article
- Prolonged Expression of a Putative Invertase Inhibitor in Micropylar Endosperm Suppressed Embryo Growth in Arabidopsis.Frontiers in plant science · 2018Article
- A Novel Imprinted Gene NUWA Controls Mitochondrial Function in Early Seed Development in Arabidopsis.PLoS genetics · 2017Article
- Quantitative Genetics Identifies Cryptic Genetic Variation Involved in the Paternal Regulation of Seed Development.PLoS genetics · 2016Article
- Evolution and function of genomic imprinting in plants.Genes & development · 2015Review
- Article
- Transcriptional silencing by polycomb-group proteins.Cold Spring Harbor perspectives in biology · 2014Review
- Epigenetic memory in plants.The EMBO journal · 2014Review
- Rice fertilization-Independent Endosperm1 regulates seed size under heat stress by controlling early endosperm development.Plant physiology · 2014Article
- Identification and characterization of the SET domain gene family in maize.Molecular biology reports · 2014Article
- The expression and roles of parent-of-origin genes in early embryogenesis of angiosperms.Frontiers in plant science · 2014Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The imprinted Arabidopsis Polycomb group (PcG) gene MEDEA (MEA), which is homologous to Enhancer of Zeste [E(Z)], is maternally required for normal seed development. Here we show that, unlike known mammalian imprinted genes, MEA regulates its own imprinted expression: It down-regulates the maternal allele around fertilization and maintains the paternal allele silent later during seed development. Autorepression of the maternal MEA allele is direct and independent of the MEA-FIE (FERTILIZATION-INDEPENDENT ENDOSPERM) PcG complex, which is similar to the E(Z)-ESC (Extra sex combs) complex of animals, suggesting a novel mechanism. A complex network of cross-regulatory interactions among the other known members of the MEA-FIE PcG complex implies distinct functions that are dynamically regulated during reproduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.