ArticlePlant physiology2006
Aging in legume symbiosis. A molecular view on nodule senescence in Medicago truncatula.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
93 citing papers in PubMed, 250 citations in OpenAlex.
- ESN3, a nodule-specific small peptide essential for symbiotic nitrogen fixation in Medicago truncatula.The New phytologist · 2026Article
- Morphology ofPlants (Basel, Switzerland) · 2025Article
- Nutrient storage and release in uninfected cells of soybean nodules support symbiotic nitrogen fixation in infected cells.aBIOTECH · 2025Article
- Maintaining sulfur supply to the symbiosome delays nodule senescence in soybean.Nature communications · 2025Article
- Uclacyanin MtUC1 Is Involved in the Regulation of Nodule Senescence in Medicago truncatula.Molecular plant pathology · 2025Article
- Diverse triggers, common outcome: Senescence in Fix⁻ Medicago truncatula nodules.Plant physiology · 2025Article
- Nutrient-dependent regulation of symbiotic nitrogen fixation in legumes.Horticulture research · 2025Article
- Inorganic nitrogen inhibits symbiotic nitrogen fixation through blocking NRAMP2-mediated iron delivery in soybean nodules.Nature communications · 2024Article
- Cyclic Isothiocyanate Goitrin ImpairsPlants (Basel, Switzerland) · 2024Article
- Host-imposed control mechanisms in legume-rhizobia symbiosis.Nature microbiology · 2024Review
- Defense and senescence interplay in legume nodules.Plant communications · 2024Review
- Metal nutrition and transport in the process of symbiotic nitrogen fixation.Plant communications · 2024Review
- VapC10 toxin of the legume symbiont Sinorhizobium meliloti targets tRNASer and controls intracellular lifestyle.The ISME journal · 2024Article
- Signaling in Legume-Rhizobia Symbiosis.International journal of molecular sciences · 2023Review
- Effects of Elevated Temperature onInternational journal of molecular sciences · 2023Article
- Effects of Elevated Temperature onInternational journal of molecular sciences · 2023Article
- GmNAC039 and GmNAC018 activate the expression of cysteine protease genes to promote soybean nodule senescence.The Plant cell · 2023Article
- Rhizobial nitrogen fixation efficiency shapes endosphere bacterial communities and Medicago truncatula host growth.Microbiome · 2023Article
- Plant-Environment Response Pathway Regulation Uncovered by Investigating Non-Typical Legume Symbiosis and Nodulation.Plants (Basel, Switzerland) · 2023Review
- Dancing to a different tune, can we switch from chemical to biological nitrogen fixation for sustainable food security?PLoS biology · 2023Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizobia reside as symbiosomes in the infected cells of legume nodules to fix atmospheric nitrogen. The symbiotic relation is strictly controlled, lasts for some time, but eventually leads to nodule senescence. We present a comprehensive transcriptomics study to understand the onset of nodule senescence in the legume Medicago truncatula. Distinct developmental stages with characteristic gene expression were delineated during which the two symbiotic partners were degraded consecutively, marking the switch in nodule tissue status from carbon sink to general nutrient source. Cluster analysis discriminated an early expression group that harbored regulatory genes that might be primary tools to interfere with pod filling-related or stress-induced nodule senescence, ultimately causing prolonged nitrogen fixation. Interestingly, the transcriptomes of nodule and leaf senescence had a high degree of overlap, arguing for the recruitment of similar pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.