Evidence map›Paper›PMID 16645239›Full record

ArticleMedical oncology (Northwood, London, England)2006

Unusual IgD+/CD38-follicular lymphoma with leukemic presentation.

Grzegorz Rymkiewicz, Ewa Paszkiewicz-Kozik, Katarzyna Blachnio, Anna Pastwiska, Jadwiga Kulik, Barbara Pienkowska-Grela, Jan Walewski

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Grzegorz RymkiewiczDepartment of Pathology, Maria Sklodowska-Curie Memorial Cancer Centre, Warsaw, Poland. grzegorzrymkiewicz@coi.waw.pl
Ewa Paszkiewicz-Kozik
Katarzyna Blachnio
Anna Pastwiska
Jadwiga Kulik
Barbara Pienkowska-Grela
Jan Walewski
The Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular lymphoma (FL) is a low-grade lymphoma, with rare presentation of leukemic phase in peripheral blood at the diagnosis. We describe a 49-yr-old woman who developed leukemic phase of FL in a 3 mo period after histological diagnosis of peripheral lymph node. To confirm the final diagnosis, flow cytometry (FCM) of peripheral blood, nested PCR with bcl-2 rearrangement, and cytogenetic analysis of peripheral blood and bone marrow cells were done. Lymphoma cells were negative for CD38 and expressed monoclonal surface immunoglobulins with relatively strong and "bright" IgD and "dim" kappa-chain by FCM analysis. Although the patient presented with generalized lymphadenopathy, massive peripheral blood and bone marrow involvement, she achieved complete clinical response after first-line chemotherapy COP and rituximab. She is still in a good condition with follow up over 2 yr.

Indexed as

ADP-ribosyl Cyclase 1Chromosome AberrationsFemaleHumansImmunoglobulin DLeukemiaLymphoma, FollicularMiddle AgedADP-ribosyl Cyclase 1Immunoglobulin D

Identifiers

PMID16645239
OpenAlexW1966302973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.