ReviewYonsei medical journal2006
Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention.
Review in Yonsei medical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 50 citations in OpenAlex.
- Assessing Cravings Among Individuals with Alcohol Dependence Syndrome Prescribed with Anti-craving Medication: A Prospective Observational Study.Indian journal of psychological medicine · 2025Article
- Video Record Viewing of Self in Delirium Tremens (VVSDT) and its Effect on Abstinence among Patients with Alcohol Dependence Syndrome.Indian journal of psychological medicine · 2024Article
- Review
- Effect of alcohol on the central nervous system to develop neurological disorder: pathophysiological and lifestyle modulation can be potential therapeutic options for alcohol-induced neurotoxication.AIMS neuroscience · 2021Review
- Alcohol Consumption, Craving, and Craving Control Efforts Assessed Daily in the Context of Readiness to Change Among Individuals with Alcohol Dependence and PTSD.Journal of substance abuse treatment · 2016Article
- Potential dual role of cephalosporins in management of alcohol use disorders.Psychopharmacology · 2014Article
- The genetics of alcoholism.Current psychiatry reports · 2009Review
- Use of Anti-Craving Agents in Soldiers with Alcohol Dependence Syndrome.Medical journal, Armed Forces India · 2008Article
- Therapeutic options and challenges for substances of abuse.Dialogues in clinical neuroscience · 2007Review
- A comparative study evaluating the efficacy of naltrexone versus acamprosate as anticraving agents in alcohol use disorder.Industrial psychiatry journalArticle
- Pharmacotherapy for relapse prevention of alcohol use disorder in the Indian setting: A systematic review.Industrial psychiatry journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors. Relapse prevention for alcohol dependence has traditionally involved psychosocial and psychotherapeutic interventions. Pharmacotherapy, however, in conjunction with behavioral therapy, is generating interest as another modality to prevent relapse and enhance abstinence. Naltrexone and acamprosate are at the forefront of the currently available pharmacological options. Naltrexone is an opioid receptor antagonist and is thought to reduce the rewarding effect of alcohol. Acamprosate normalizes the dysregulation of N-methyl-D- aspartate (NMDA)-mediated glutamatergic excitation that occurs in alcohol withdrawal and early abstinence. These different mechanisms of action and different target neurotransmitter systems may endow the two drugs with efficacy for different aspects of alcohol use behavior. Since not all patients seem to benefit from naltrexone and acamprosate, there are ongoing efforts to improve the treatment outcomes by examining the advantages of combined pharmacotherapy and exploring the variables that might predict the response of the medications. In addition, novel medications are being investigated to assess their efficacy in preventing relapse and increasing abstinence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.