Evidence map›Paper›PMID 16641460›Full record

ArticleAntimicrobial agents and chemotherapy2006

Streptococcus pneumoniae isolates resistant to telithromycin.

M Rantala, M Haanperä-Heikkinen, M Lindgren, H Seppälä, P Huovinen, J Jalava

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Newer antibacterial drugs for a new century.Expert opinion on investigational drugs · 2010
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

M RantalaLaboratory of Human Microbial Ecology, National Public Health Institute, Kiinamyllynkatu 13, FIN-20520 Turku, Finland. merja.rantala@ktl.fi
M Haanperä-Heikkinen
M Lindgren
H Seppälä
P Huovinen
J Jalava
Turku City Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The telithromycin susceptibility of 210 erythromycin-resistant pneumococci was tested with the agar diffusion method. Twenty-six erm(B)-positive isolates showed heterogeneous resistance to telithromycin, which was manifested by the presence of colonies inside the inhibition zone. When these cells were cultured and tested, they showed stable, homogeneous, and high-level resistance to telithromycin.

Indexed as

Anti-Bacterial AgentsBase SequenceDrug Resistance, MicrobialGenes, BacterialHumansKetolidesMacrolidesMicrobial Sensitivity TestsMolecular Sequence DataPromoter Regions, GeneticStreptococcus pneumoniaeAnti-Bacterial AgentsKetolidesMacrolidestelithromycin

Identifiers

PMID16641460
PMCPMC1472201
OpenAlexW2161157728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.