Evidence map›Paper›PMID 16640963›Full record

ReviewCurrent atherosclerosis reports2006

Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury.

Neeta Adhikari, Nathan Charles, Ute Lehmann, Jennifer L Hall

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Does HSP90 play an important role in psoriasis?Postepy dermatologii i alergologii · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Therapeutic effects of suppressors of cytokine signaling in diabetic nephropathy.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2014
    Article
  16. Article
  17. Article
  18. Article
  19. Suppressors of cytokine signaling abrogate diabetic nephropathy.Journal of the American Society of Nephrology : JASN · 2010
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Neeta AdhikariCardiovascular Division, University of Minnesota, Mayo Mail Code 508, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Nathan Charles
Ute Lehmann
Jennifer L Hall
University of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our understanding of the molecular signaling pathways regulating the initiation and progression of atherosclerosis or remodeling in response to injury has begun to cross the boundaries from regulation of well-described canonical pathways to the interplay between these pathways. The focus of this review is to summarize our current understanding of a finite group of transcription factors and kinases involved in vascular injury and atherosclerosis, including nuclear factor-kappaB (NF-kappaB), early growth response factor-1 (Egr-1), activator protein-1 (AP-1), hypoxia inducible factor-1alpha (HIF-1alpha), homeobox, and T cell factor/lymphoid enhancer factor (Tcf-Lef), as well as the kinases janus kinase/signal transducers and activators of transcription (JAK/STAT), protein kinase C (PKC), p38, Rho, ERK5, JNK, p44/p42, and phosphoinositide 3 (PI3) kinase/AKT.

Indexed as

AnimalsAtherosclerosisHumansHypoxia-Inducible Factor 1, alpha SubunitModels, BiologicalNF-kappa BPhosphotransferasesSignal TransductionTranscription FactorsTranscription, GeneticVascular DiseasesHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitNF-kappa BPhosphotransferasesTranscription Factors

Identifiers

PMID16640963
OpenAlexW1976915500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.