ReviewCurrent atherosclerosis reports2006
Oxidized lipids: the two faces of vascular inflammation.
Review in Current atherosclerosis reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Mechanisms of Yiqi Huoxue Granule in Atherosclerosis Treatment: Insights from UPLC-Q-Exactive Orbitrap-MS Analysis, Network Pharmacology, Molecular Docking, and Experimental Verification.Journal of inflammation research · 2026Article
- The role of inflammation and the possibilities of inflammation reduction to prevent cardiovascular events.European heart journal open · 2022Review
- Oxidized Phospholipids in Control of Endothelial Barrier Function: Mechanisms and Implication in Lung Injury.Frontiers in endocrinology · 2021Review
- Lipid Oxidation Products on Inflammation-Mediated Hypertension and Atherosclerosis: A Mini Review.Frontiers in nutrition · 2021Review
- Association Between Oxidation-Modified Lipoproteins and Coronary Plaque in Psoriasis.Circulation research · 2018Article
- Lipid mediators in the regulation of endothelial barriers.Tissue barriers · 2018Review
- Oxidized phospholipids are ligands for LRP6.Bone research · 2018Article
- Influence of α-lipoic Acid on Morphology of Organs of Rabbits Fed a High Fat Diet with the Addition of Oxidised Rapeseed Oil.Journal of veterinary research · 2017Article
- The arterial microenvironment: the where and why of atherosclerosis.The Biochemical journal · 2016Review
- Article
- Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase.American journal of physiology. Heart and circulatory physiology · 2014Article
- Immune mechanisms in atherosclerosis, especially in diabetes type 2.Frontiers in endocrinology · 2013Review
- Fragmented oxidation products define barrier disruptive endothelial cell response to OxPAPC.Translational research : the journal of laboratory and clinical medicine · 2013Article
- Article
- Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells.PPAR research · 2011Article
- Oxidized LDL: diversity, patterns of recognition, and pathophysiology.Antioxidants & redox signaling · 2010Review
- Oxidized low-density lipoprotein.Methods in molecular biology (Clifton, N.J.) · 2010Review
- Immunohistochemical detection of 13(R)-hydroxyoctadecadienoic acid in atherosclerotic plaques of human carotid arteries using a novel specific antibody.Acta histochemica et cytochemica · 2009Article
- Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.Circulation research · 2009Article
- Oxidized phospholipids in control of inflammation and endothelial barrier.Translational research : the journal of laboratory and clinical medicine · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Elevated plasma levels of low-density lipoprotein and generation of oxidized low-density lipoprotein have been directly associated with the pathogenesis of atherosclerosis, and lipid oxidation products have been directly linked with induction and propagation of monocytic subendothelial accumulation and other inflammatory reactions associated with chronic vascular inflammation. However, accumulating data suggest that oxidized lipids may also exhibit anti-inflammatory potential and serve as potent inhibitors of nuclear factor-kappaB-dependent proinflammatory cascade. In addition, we have characterized a group of bioactive components of oxidized phospholipids with barrier-protective effects towards endothelial cells in the models of agonist-induced endothelial permeability and lipopolysaccharide-induced lung dysfunction. This review discusses the role of oxidized lipids in the progression of atherosclerosis as well as the important anti-inflammatory effects of oxidized phospholipids and their potential role in the modulation of vascular barrier integrity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.