ReviewJournal of anatomy2006
How nutrition and exercise maintain the human musculoskeletal mass.
Review in Journal of anatomy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- High-Protein Energy-Restriction: Effects on Body Composition, Contractile Properties, Mood, and Sleep in Active Young College Students.Frontiers in sports and active living · 2021Article
- Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss.GeroScience · 2020Review
- The association between dietary acid load and muscle strength among Iranian adults.BMC research notes · 2020Article
- Exercise Training, Intermittent Fasting and Alkaline Supplementation as an Effective Strategy for Body Weight Loss: A 12-Week Placebo-Controlled Double-Blind Intervention with Overweight Subjects.Life (Basel, Switzerland) · 2020Article
- Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy.Journal of cancer research and clinical oncology · 2019Article
- The relationships and interactions between age, exercise and physiological function.The Journal of physiology · 2019Review
- Sex differences in the response to resistance exercise training in older people.Physiological reports · 2016Article
- A higher alkaline dietary load is associated with greater indexes of skeletal muscle mass in women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
- Protein turnover, amino acid requirements and recommendations for athletes and active populations.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2012Review
- MTOR signaling and ubiquitin-proteosome gene expression in the preservation of fat free mass following high protein, calorie restricted weight loss.Nutrition & metabolism · 2012Article
- Muscle protein synthesis in response to nutrition and exercise.The Journal of physiology · 2012Review
- Use of cis-[18F]fluoro-proline for assessment of exercise-related collagen synthesis in musculoskeletal connective tissue.PloS one · 2011Article
- Biochemical and pharmacological characterization of different recombinant acid alpha-glucosidase preparations evaluated for the treatment of Pompe disease.Molecular genetics and metabolism · 2008Article
- Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis.European journal of applied physiology · 2008Review
- Comparison of body composition between professional sportswomen and apparently healthy age- and sex-matched controls.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
In this article we review some of our recent work concerning the effects of nutrition and exercise on protein synthesis and signal transduction in human musculoskeletal tissues. A great deal of new information is being generated by the application of recently refined techniques for measuring protein turnover. The field remains one that is largely descriptive but increasingly we are beginning to discern mechanisms underlying lean tissue maintenance, growth and wasting especially as multidisciplinary tools are applied to its study. Several types of exercise and nutrition are potent stimuli for protein synthesis in skeletal muscle. By contrast, collagen in the extracellular matrix in muscle and tendon appears to be mechanically but not nutritionally sensitive. The rates of collagen turnover in a variety of tissues are sufficiently high to account for a sizeable proportion of whole body protein turnover. One of the most recent surprises is the high turnover rate of human bone collagen and its anabolic response to feeding. As our understanding of the normal physiology of these processes advances, we become better able to construct testable hypotheses concerning the effects of ageing and disease on the musculoskeletal mass. Current evidence suggests that one of the major problems with loss of muscle during ageing is an inability of the tissue to respond adequately to increased availability of nutrients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.