ReviewJournal of molecular neuroscience : MN2006
Motoneuron injury and repair: New perspectives on gonadal steroids as neurotherapeutics.
Review in Journal of molecular neuroscience : MN, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Predictors of treatment failure 24 months after surgery for stress urinary incontinence.The Journal of urology · 2008Trial
- Androgens mediate sexual dimorphism in Pilarowski-Bjornsson syndrome.American journal of human genetics · 2026Article
- The association between cardiorespiratory fitness and resting-state functional connectivity in adults with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men.GeroScience · 2022Article
- Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1Frontiers in endocrinology · 2022Article
- Decreased Level of Neurotrophic Factor Neuritin 1 in Women with Ovarian Endometriosis after Receiving Gonadotropin-Releasing Hormone Agonist Treatment.International journal of molecular sciences · 2019Article
- Neuroprotective effects of estradiol on motoneurons in a model of rat spinal cord embryonic explants.Cellular and molecular neurobiology · 2013Article
- Immune cell-mediated neuroprotection is independent of estrogen action through estrogen receptor-alpha.Metabolic brain disease · 2012Article
- The function of activity-regulated genes in the nervous system.Physiological reviews · 2009Review
- Neuroprotective effect of testosterone treatment on motoneuron recruitment following the death of nearby motoneurons.Developmental neurobiology · 2009Article
- Neuroprotective actions of androgens on motoneurons.Frontiers in neuroendocrinology · 2009Review
- Androgen regulation of axon growth and neurite extension in motoneurons.Hormones and behavior · 2008Review
- Androgen cell signaling pathways involved in neuroprotective actions.Hormones and behavior · 2008Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this review, we will summarize recent work from our laboratory on the role of gonadal steroids as neuroprotective agents in motoneuron viability following cell stress. Three motoneuron models will be discussed: developing axotomized hamster facial motoneurons (FMNs); adult axotomized mouse FMNs; and immortalized, cultured mouse spinal motoneurons subjected to heat shock. New work on two relevant motoneuron proteins, the survival of motor neuron protein, and neuritin or candidate plasticity-related gene 15, indicates differential steroid regulation of these two proteins after axotomy. The concept of gonadal steroids as cellular stress correction factors and the implications of this for acute neurological injury situations will be presented as well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.