ReviewArchives of disease in childhood. Fetal and neonatal edition2006
Minimising ventilator induced lung injury in preterm infants.
Review in Archives of disease in childhood. Fetal and neonatal edition, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Flow-cycled Ventilation in Preterm Infants (FLIPI): A Pilot Study Looking at the Tolerance of Flow-cycled Ventilation by Preterm Infants With Respiratory Distress Syndrome
Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extubation
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Flow-cycled versus time-cycled synchronized ventilation for neonates.The Cochrane database of systematic reviews · 2010Pooled it
- Comparison of extubation success using noninvasive positive pressure ventilation (NIPPV) versus noninvasive neurally adjusted ventilatory assist (NI-NAVA).Journal of perinatology : official journal of the California Perinatal Association · 2020Trial
- Non-invasive high-frequency ventilation versus bi-phasic continuous positive airway pressure (BP-CPAP) following CPAP failure in infants <1250 g: a pilot randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2017Trial
- Nasal high-frequency ventilation for premature infants.Acta paediatrica (Oslo, Norway : 1992) · 2008Trial
- Feasibility of lung ultrasound-guided positive end-expiratory pressure adjustment in newborns.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Neurally Adjusted Ventilatory Assist Compared with Volume-Targeted and Pressure-Controlled Modes in Preterm Infants with Respiratory Distress Syndrome.Journal of clinical medicine · 2026Article
- Ventilation strategies and risk factors for intraoperative respiratory critical events and postoperative pulmonary complications in neonates and small infants: a secondary analysis of the NECTARINE cohortBritish journal of anaesthesia · 2025Observational
- Systemic heparin administration impairs lung development in neonatal mice.Scientific reports · 2025Article
- Laryngeal Mask for Minimally-invasive Surfactant Administration: A Narrative Review.Current pediatric reviews · 2025Review
- Article
- Less Invasive Surfactant Administration: A Viewpoint.American journal of perinatology · 2024Review
- Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants.The Cochrane database of systematic reviews · 2023Review
- Caffeine versus aminophylline in combination with oxygen therapy for apnea of prematurity: A retrospective cohort study.Experimental and therapeutic medicine · 2020Article
- How to ventilate preterm infants with lung compliance close to circuit compliance: real-time simulations on an infant hybrid respiratory simulator.Medical & biological engineering & computing · 2020Article
- Comparison of NIV-NAVA and NCPAP in facilitating extubation for very preterm infants.BMC pediatrics · 2019Article
- A new infant hybrid respiratory simulator: preliminary evaluation based on clinical data.Medical & biological engineering & computing · 2017Article
- A translational cellular model to study the impact of high-frequency oscillatory ventilation on human epithelial cell function.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Increased airway reactivity in a neonatal mouse model of continuous positive airway pressure.Pediatric research · 2015Article
- Neurally adjusted ventilator assist in very low birth weight infants: Current status.World journal of methodology · 2015Article
- Volume guarantee pressure support ventilation in extremely preterm infants and neurodevelopmental outcome at 18 months.Journal of perinatology : official journal of the California Perinatal Association · 2015Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the "new BPD" may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.