Evidence map›Paper›PMID 16628388›Full record

ArticleJournal of digital imaging2006

Computerized digital imaging techniques provided by digital X-ray radiogrammetry as new diagnostic tool in rheumatoid arthritis.

Joachim Böttcher, Alexander Pfeil, Anders Rosholm, Max-Ludwig Schäfer, Ansgar Malich, Alexander Petrovitch, Bettina Seidl, Gabriele Lehmann, Hans-Joachim Mentzel, Gert Hein and 2 more

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In one paragraph

Article in Journal of digital imaging, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

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  8. Influence of angulation on metacarpal bone mineral density measurements using digital X-ray radiogrammetry.International journal of computer assisted radiology and surgery · 2015
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  9. Quantification of periarticular demineralization and synovialitis of the hand in rheumatoid arthritis patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012
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  11. Using hand bone mass measurements to assess progression of rheumatoid arthritis.Therapeutic advances in musculoskeletal disease · 2010
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Joachim BöttcherInstitute of Diagnostic and Interventional Radiology, Friedrich-Schiller University Jena, Erlanger Allee 101, 07747, Jena, Germany. joachim.boettcher@med.uni-jena.de
Alexander Pfeil
Anders Rosholm
Max-Ludwig Schäfer
Ansgar Malich
Alexander Petrovitch
Bettina Seidl
Gabriele Lehmann
Hans-Joachim Mentzel
Gert Hein
Gunter Wolf
Werner A Kaiser
Friedrich Schiller University Jena · DESectra (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur study evaluates digital x-ray radiogrammetry (DXR) and Radiogrammetry Kit (RK) as a new diagnostic method for the measurement of disease-related osteoporosis including quantification of joint space narrowing dependent on the severity of rheumatoid arthritis (RA). MATERIALS AND

methodsA total of 172 unselected patients with RA underwent computerized measurements of bone mineral density (BMD) and metacarpal index (MCI) by DXR, as well as a semiautomated measurement of joint space distances at the metacarpal-phalangeal articulation (JSD-MCP 2-5), both were analyzed from plain radiographs of the nondominant hand.

resultsCorrelations between DXR-BMD and DXR-MCI vs. parameters of RK were all significant (0.34 < R < 0.61; p < 0.01). An expected negative association was observed between RK parameters and the different scoring methods (-0.27 < R < -0.59). The maximum relative decrease in BMD vs. MCI as measured by DXR between the highest and lowest RA severity group was -27.7% vs. -27.5% (p < 0.01) for the modified Larsen Score, whereas the minimal value of relative DXR-BMD and DXR-MCI reduction could be documented for the Sharp Erosion Score (-20.8% vs. -26.8%; p < 0.01). The relative reduction of mean JSD-MCP using RK significantly varied from -25.0% (Sharp Erosion Score) to -41.2% (modified Larsen Score). In addition, an excellent reproducibility of DXR and RK could be verified.

conclusionDXR in combination with RK could be a promising, widely available diagnostic tool to supplement the different scoring methods of RA with quantitative data, allowing an earlier and improved diagnosis and more precision in determining disease progression.

Indexed as

Radiographic Image EnhancementAdolescentAdultAgedAged, 80 and overArthritis, RheumatoidBone DensityDisease ProgressionFemaleHand BonesHand JointsHumansMaleMiddle AgedOsteoporosisReproducibility of Results

Identifiers

PMID16628388
PMCPMC3045148
OpenAlexW2024268876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.