ArticleInternational urogynecology journal and pelvic floor dysfunction2007
A 3-month preclinical trial to assess the performance of a new TVT-like mesh (TVTx) in a sheep model.
Article in International urogynecology journal and pelvic floor dysfunction, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 45 citations in OpenAlex.
- Comparison of three mid-urethral tension-free tapes (TVT, TVT-O, and TVT-Secur) in the treatment of female stress urinary incontinence: 1-year follow-up.International urogynecology journal · 2011Trial
- Short-term outcomes with the Ajust™ system: a new single incision sling for the treatment of stress urinary incontinence.International urogynecology journal · 2011Trial
- TVT-S for surgical treatment of stress urinary incontinence: prospective trial, 1-year follow-up.International urogynecology journal · 2010Trial
- Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease.Orphanet journal of rare diseases · 2015Review
- Short-term outcomes of Altis single-incision sling procedure for stress urinary incontinence: a prospective single-center study.International urogynecology journal · 2014Observational
- Animal models of female pelvic organ prolapse: lessons learned.Expert review of obstetrics & gynecology · 2012Article
- TVT SECUR System: Final results of a prospective, observational, multicentric study.International urogynecology journal · 2012Article
- TVT-S in the U position--anatomical study.International urogynecology journal · 2011Article
- Experience with TVT-SECUR sling for stress urinary incontinence: a 141-case analysis.International urogynecology journal · 2010Article
- Anatomical relationship and fixation of tension-free vaginal tape Secur.International urogynecology journal and pelvic floor dysfunction · 2009Article
- Correlation between changes in ultrasound measurements and clinical curative effect of tension-free vaginal tape-SECUR* procedure.International urogynecology journal and pelvic floor dysfunction · 2009Article
- TVT-secur: a minimally invasive procedure for the treatment of primary stress urinary incontinence. One year data from a multi-centre prospective trial.International urogynecology journal and pelvic floor dysfunction · 2009Article
- Tissue resistance of the tension-free procedure: what about healing?International urogynecology journal and pelvic floor dysfunction · 2008Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to evaluate in a sheep model the performance of a new polypropylene mesh (TVTx), which is intended as a less invasive treatment for female stress urinary incontinence. Eight female sheep were used in this study, each one being implanted with eight TVTx samples. At each time-point (weeks 1, 2, 4, and 12) seven TVTx were pulled out, while one TVTx was carefully dissected for histological investigations. One TVTx and one TVT, moreover, were inserted and immediately pulled out for obtaining the initial pullout forces in all sheep. The initial pullout values of TVT and TVTx were overlapping. The pullout forces of TVTx were >5 N (500 g) and increasing from weeks 1 to 12 (p<0.001). Histology revealed good tissue integration of TVTx in the tissue within 12 weeks after implantation. No abnormal histological findings were observed. This data could support the realization of a clinical trial with the TVTx mesh.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.