Evidence map›Paper›PMID 16627509›Full record

Trial reportBMJ (Clinical research ed.)2006

Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial.

Doris Staab, Thomas L Diepgen, Manigé Fartasch, Jörg Kupfer, Thomas Lob-Corzilius, Johannes Ring, Sibylle Scheewe, Reginald Scheidt, Gerhard Schmid-Ott, Christina Schnopp and 5 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. European S2k Guideline on Chronic PruritusActa dermato-venereologica · 2025
    Guideline
  4. Pooled it
  5. Pooled it
  6. Supporting families managing childhood eczema: developing and optimising eczema care online using qualitative research.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Pooled it
  7. Pooled it
  8. Effects of caregiver-involved interventions on the quality of life of children and adolescents with chronic conditions and their caregivers: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Pooled it
  9. Pooled it
  10. Psychological and educational interventions for atopic eczema in children.The Cochrane database of systematic reviews · 2014
    Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. [Patient education for adults with atopic dermatitis according to the ARNE concept].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018
    Trial
  15. Trial
  16. Trial
  17. A randomised controlled trial into the effects of food on ADHD.European child & adolescent psychiatry · 2009
    Trial
  18. Trial
  19. Review
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Doris StaabDepartment of Paediatric Pulmonology and Immunology, Charité, Humboldt University, Berlin.
Thomas L Diepgen
Manigé Fartasch
Jörg Kupfer
Thomas Lob-Corzilius
Johannes Ring
Sibylle Scheewe
Reginald Scheidt
Gerhard Schmid-Ott
Christina Schnopp
Rüdiger Szczepanski
Thomas Werfel
Marita Wittenmeier
Ulrich Wahn
Uwe Gieler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effects of age related, structured educational programmes on the management of moderate to severe atopic dermatitis in childhood and adolescence.

designMulticentre, randomised controlled trial.

settingSeven hospitals in Germany.

participantsParents of children with atopic dermatitis aged 3 months to 7 years (n = 274) and 8-12 years (n = 102), adolescents with atopic dermatitis aged 13-18 years (n = 70), and controls (n = 244, n = 83, and n = 50, respectively).

interventionsGroup sessions of standardised intervention programmes for atopic dermatitis once weekly for six weeks or no education (control group).

main outcome measuresSeverity of eczema (scoring of atopic dermatitis scale), subjective severity (standardised questionnaires), and quality of life for parents of affected children aged less than 13 years, over 12 months.

resultsSignificant improvements in severity of eczema and subjective severity were seen in all intervention groups compared with control groups (total score for severity: age 3 months to 7 years - 17.5, 95% confidence intervals - 19.6 to - 15.3 v - 12.2, - 14.3 to - 10.1; age 8-12 years - 16.0, - 20.0 to - 12.0 v - 7.8, - 11.4; - 4.3; and age 13-18 years - 19.7, - 23.7 to - 15.7 v - 5.2, - 10.5 to 0.1). Parents of affected children aged less than 7 years experienced significantly better improvement in all five quality of life subscales, whereas parents of affected children aged 8-12 years experienced significantly better improvement in three of five quality of life subscales.

conclusionAge related educational programmes for the control of atopic dermatitis in children and adolescents are effective in the long term management of the disease.

Indexed as

AdolescentChildChild, PreschoolDermatitis, AtopicGermanyHumansInfantParentsPatient Education as TopicPruritusQuality of LifeSelf CareSeverity of Illness IndexSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID16627509
PMCPMC1444870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.