Evidence map›Paper›PMID 16625620›Full record

SynthesisThe Cochrane database of systematic reviews2006

Total versus subtotal hysterectomy for benign gynaecological conditions.

A Lethaby, V Ivanova, N P Johnson

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01825915 (Feasibility of a Randomised Controlled Trial of Laparoscopic Hysterectomy Versus Laparoscopic Sub-Total Hysterectomy), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01825915 naunknown statusnot on this mapstarted 2010, after this paper: background citation

Feasibility of a Randomised Controlled Trial of Laparoscopic Hysterectomy Versus Laparoscopic Sub-Total Hysterectomy

TypeinterventionalSponsorMedway NHS Foundation TrustRan2010 to 2013Enrolled50ConditionsBenign Disease of the UterusArmsLaparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 213 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Supracervical hysterectomy - the vaginal route.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2014
    Article
  8. Article
  9. Hysterectomy-a comparison of approaches.Deutsches Arzteblatt international · 2010
    Article
  10. Article
  11. Long-Term Outcomes of the Total or Supracervical Hysterectomy (TOSH) Trial.Female pelvic medicine & reconstructive surgery · 2010
    Article
  12. Review of current status of female sexual dysfunction evaluation in urogynecology.International urogynecology journal and pelvic floor dysfunction · 2009
    Review
  13. Efficacy of laparoscopic sacrocervicopexy for apical support of pelvic organ prolapse.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
  14. Laparoscopic supracervical hysterectomy compared to total hysterectomy.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
  15. Supracervical robotic-assisted laparoscopic sacrocolpopexy for pelvic organ prolapse.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
  16. Laparoscopic supracervical hysterectomy for benign gynecologic conditions.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

A LethabySchool of Population Health, Section of Epidemiology and Biostatistics (Level four), Tamaki Campus, University of Auckland, Private Bag 92019, Auckland, New Zealand. a.lethaby@auckland.ac.nz
V Ivanova
N P Johnson
University of Auckland · NZWomen's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHysterectomy using an abdominal approach removes either the uterus alone (subtotal hysterectomy) or both the uterus and the cervix (total hysterectomy). The latter is more common but outcomes have not been systematically compared.

objectivesTo assess and compare outcomes with subtotal hysterectomy versus total abdominal hysterectomy for benign gynaecological conditions. SEARCH STRATEGY: We searched the Cochrane Menstrual Disorders and Subfertility Group's specialised register of controlled trials (December 2005), Central (December 2005), Medline (1966 to December 2005), EmBase (1980 to December 2005), Biological Abstracts (1980 to December 2005), the National Research Register and relevant citation lists. SELECTION CRITERIA: Only randomised controlled trials of women undergoing either total or subtotal hysterectomy for benign gynaecological conditions were included. DATA COLLECTION AND ANALYSIS: Three trials that included 733 participants were included. Independent selection of trials and data extraction were undertaken by 2 reviewers and results compared. MAIN

resultsThere was no evidence of a difference in the rates of incontinence, constipation or measures of sexual function. In one unblinded trial, a significantly greater proportion of women indicated that they had frequent episodes of urinary incontinence after subtotal hysterectomy when compared with total hysterectomy (OR=2.1, 1.02 to 4.3), but these results were not confirmed by the other two trials that measured both stress and urge incontinence and urinary frequency. . Length of surgery and amount of blood lost during surgery were significantly reduced during subtotal hysterectomy when compared with total hysterectomy, but there was no evidence of a difference in the odds of transfusion. Febrile morbidity was less likely (OR=0.43, 0.25 to 0.75) and ongoing cyclical vaginal bleeding one year after surgery was more likely (OR=11.3, 4.1 to 31.2) after subtotal when compared with total hysterectomy. There was no evidence of a difference in the rates of other complications, recovery from surgery or readmission rates. AUTHORS'

conclusionsThis review has not confirmed the perception that subtotal hysterectomy offers improved outcomes for sexual, urinary or bowel function when compared with total abdominal hysterectomy. Surgery is shorter and intraoperative blood loss and fever are reduced but women are more likely to experience ongoing cyclical bleeding up to a year after surgery with subtotal hysterectomy compared to total hysterectomy.

Indexed as

Blood Loss, SurgicalCoitusFemaleHumansHysterectomyHysterectomy, VaginalLeiomyomaMenorrhagiaQuality of LifeRandomized Controlled Trials as TopicUrination Disorders

Identifiers

PMID16625620
OpenAlexW2108080908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.