Evidence map›Paper›PMID 16625396›Full record

ArticleRadiation and environmental biophysics2006

No effect of pulsed electromagnetic fields on PC12 and HL-60 cells.

W Sontag, D Kalka

Abstract read
PubMed Publisher
In one paragraph

Article in Radiation and environmental biophysics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Repetitive magnetic stimulation promotes neural stem cells proliferation by upregulating MiR-106b in vitro.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015
    Article
  3. Repetitive magnetic stimulation of human-derived neuron-like cells activates cAMP-CREB pathway.European archives of psychiatry and clinical neuroscience · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

W SontagForschungszentrum Karlsruhe, Institut für Biologische Grenzflächen, Postfach 3640, 76021 Karlsruhe, Germany. sontag@ibg.fzk.de
D Kalka
FZI Research Center for Information Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of pulsed electromagnetic fields (PEMF) similar to those used in transcranial magnetic stimulation (TMS) on two tumour cell lines, the human promyelocytic leukaemia cell line (HL-60) and the rat pheochromocytoma cell line (PC12), was investigated. The two cell lines were exposed to non-homogeneous pulsed electromagnetic fields (about 0.25-4.5 T peak magnetic field strength; 1-8 exponential pulses, 0.25 Hz) at different positions on the coil (2x25 mm). After exposure with various intensities, various numbers of pulses and at different coil positions, cell viability and the intracellular cyclic AMP content were determined in the two cell lines. Additionally, in HL-60 cells the intracellular Hsp72 content and in PC12 cells the release of the neurotransmitters dopamine, noradrenaline and acetylcholine were measured after PEMF treatment. The results of these analyses do not hint at alterations in the cell viability or in the content of cAMP, Hsp72, dopamine, noradrenaline, and acetylcholine in the two tumour cell lines after PEMF exposure under various conditions.

Indexed as

Electromagnetic FieldsAcetylcholineAnimalsCell SurvivalCholinergic AgentsCyclic AMPDopamineHL-60 CellsHSP72 Heat-Shock ProteinsHumansNeurotransmitter AgentsNorepinephrinePC12 CellsRatsAcetylcholineCholinergic AgentsCyclic AMPDopamineHSP72 Heat-Shock ProteinsNeurotransmitter AgentsNorepinephrine

Identifiers

PMID16625396
OpenAlexW1988457983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.