Evidence map›Paper›PMID 16622254›Full record

ArticleInfection and immunity2006

Modification of a mammalian cell protein in the presence of [32P-adenylate]NAD: evidence for ADP ribosylation activity associated with Helicobacter pylori.

Carlos W Nossa, Steven R Blanke

Abstract read
In one paragraph

Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carlos W NossaDepartment of Microbiology, University of Illinois, 601 South Goodwin Ave., Urbana, IL 61801, USA.
Steven R Blanke

Funding

MOLECULAR MECHANISMS OF THE H. PYLORI VACUOLATING TOXINR01AI045928 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI BLANKE, STEVEN R. · 2000 to 2010
$1.9M
Molecular Mechanisms of the H. pylori Vacuolating ToxinR56AI045928 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BLANKE, STEVEN R. · 2011 to 2011
$254k
NIAID NIH HHS AI045928NIAID NIH HHS R01 AI045928NIAID NIH HHS R56 AI045928
6 · The paper itself

Abstract

Culture filtrates from Helicobacter pylori promote the transfer of the radiolabel from [32P-adenylate]NAD to one or more heat-labile factors within extracts prepared from several mammalian cell lines, with the predominate radiolabeled species exhibiting an apparent molecular mass of greater than 130 kDa. Our results suggest that several H. pylori strains release a factor that ADP-ribosylates a mammalian target protein.

Indexed as

ADP Ribose TransferasesHeLa CellsHelicobacter pyloriHumansNADPhosphorus RadioisotopesProteinsADP Ribose TransferasesNADPhosphorus RadioisotopesProteins

Identifiers

PMID16622254
PMCPMC1459732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.