ArticlePLoS biology2006
Parallel evolution of the genetic code in arthropod mitochondrial genomes.
Article in PLoS biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Gene Rearrangement in the Mitochondrial Genomes of the Sand Crabs Albunea symmysta (Anomura:Hippoidea) with Insights into Phylogenetic Relationships in the Anomura (Crustacea: Decapoda).Biochemical genetics · 2026Article
- The first mitochondrial genome for Sterictiphorinae (Hymenoptera: Argidae) and insights into argid phylogeny.Scientific reports · 2026Article
- Complete Mitochondrial Genome Sequencing ofBiology · 2025Article
- Comparative Analysis of Mitogenomes in Leafhopper Tribe Deltocephalini (Hemiptera: Cicadellidae: Deltocephalinae): Structural Conservatism and Phylogeny.Ecology and evolution · 2024Article
- Aberrant Mitochondrial tRNA Genes Appear Frequently in Animal Evolution.Genome biology and evolution · 2024Article
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- The Tardigrade damage suppressor protein Dsup promotes DNA damage in neurons.Molecular and cellular neurosciences · 2023Article
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- The complete mitochondrial genome of the woodwasp Euxiphydria potanini (Hymenoptera, Xiphydrioidea) and phylogenetic implications for symphytans.Scientific reports · 2022Article
- Characterizing the Complete Mitochondrial Genome of Arma custos and Picromerus lewisi (Hemiptera: Pentatomidae: Asopinae) and Conducting Phylogenetic Analysis.Journal of insect science (Online) · 2022Article
- Two Complete Mitogenomes of Chalcididae (Hymenoptera: Chalcidoidea): Genome Description and Phylogenetic Implications.Insects · 2021Article
- Article
- Article
- Two Complete Mitochondrial Genomes of Mileewinae (Hemiptera: Cicadellidae) and a Phylogenetic Analysis.Insects · 2021Article
- Improved annotation of protein-coding genes boundaries in metazoan mitochondrial genomes.Nucleic acids research · 2019Article
- Evolution and Unprecedented Variants of the Mitochondrial Genetic Code in a Lineage of Green Algae.Genome biology and evolution · 2019Article
- Review
- Rapid Genetic Code Evolution in Green Algal Mitochondrial Genomes.Molecular biology and evolution · 2019Article
- Complete mitogenome ofPeerJ · 2019Article
- Mitogenomics Reveals a Novel Genetic Code in Hemichordata.Genome biology and evolution · 2019Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The genetic code provides the translation table necessary to transform the information contained in DNA into the language of proteins. In this table, a correspondence between each codon and each amino acid is established: tRNA is the main adaptor that links the two. Although the genetic code is nearly universal, several variants of this code have been described in a wide range of nuclear and organellar systems, especially in metazoan mitochondria. These variants are generally found by searching for conserved positions that consistently code for a specific alternative amino acid in a new species. We have devised an accurate computational method to automate these comparisons, and have tested it with 626 metazoan mitochondrial genomes. Our results indicate that several arthropods have a new genetic code and translate the codon AGG as lysine instead of serine (as in the invertebrate mitochondrial genetic code) or arginine (as in the standard genetic code). We have investigated the evolution of the genetic code in the arthropods and found several events of parallel evolution in which the AGG codon was reassigned between serine and lysine. Our analyses also revealed correlated evolution between the arthropod genetic codes and the tRNA-Lys/-Ser, which show specific point mutations at the anticodons. These rather simple mutations, together with a low usage of the AGG codon, might explain the recurrence of the AGG reassignments.
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