ArticleProceedings. Biological sciences2006
Disease ecology in the Galápagos Hawk (Buteo galapagoensis): host genetic diversity, parasite load and natural antibodies.
Article in Proceedings. Biological sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 202 citations in OpenAlex.
- Hepatozoon (Eucoccidiorida: Hepatozoidae) in wild mammals of the Americas: a systematic review.Parasites & vectors · 2024Pooled it
- Host genetic diversity limits parasite success beyond agricultural systems: a meta-analysis.Proceedings. Biological sciences · 2019Pooled it
- Parasite-mediated inbreeding depression in wild red deer.Heredity · 2025Article
- Incipient Genetic Differentiation of the African Buffalo,Ecology and evolution · 2025Article
- The shape of discovery: a journey through genetics, coevolution, and a scientific life.Genetics · 2025Article
- Road to Extinction? Past and Present Population Structure and Genomic Diversity in the Koala.Molecular biology and evolution · 2025Article
- Host genetic diversity and body condition influence parasite resistance and clearance in a wild marine mammal population.Biology letters · 2024Article
- Antigen specificity affects analysis of natural antibodies.Frontiers in immunology · 2024Article
- Infectious disease as a driver of declines and extinctions.Cambridge prisms. Extinction · 2024Review
- Race-specific association of an IRGM risk allele with cytokine expression in human subjects.Scientific reports · 2023Article
- Host genetic identity determines parasite community structure across time and space in oyster restoration.Proceedings. Biological sciences · 2023Article
- Leveraging an existing whole-genome resequencing population data set to characterize toll-like receptor gene diversity in a threatened bird.Molecular ecology resources · 2022Article
- Dynamics of reduced genetic diversity in increasingly fragmented populations of Florida scrub jays,Evolutionary applications · 2022Article
- Identification of candidate genes associated with bacterial and viral infections in wild boars hunted in Tuscany (Italy).Scientific reports · 2022Article
- Challenging a host-pathogen paradigm: Susceptibility to chytridiomycosis is decoupled from genetic erosion.Journal of evolutionary biology · 2022Article
- Genetic diversity and disease: The past, present, and future of an old idea.Evolution; international journal of organic evolution · 2022Article
- The Patterns and Causes of Dermatitis in Terrestrial and Semi-Aquatic Mammalian Wildlife.Animals : an open access journal from MDPI · 2021Review
- Does genetic diversity protect host populations from parasites? A meta-analysis across natural and agricultural systems.Evolution letters · 2021Article
- Article
- Advances in the Development of Anti-Vaccines · 2020Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Galápagos endemic bird, providing the context for a natural experiment examining the effects of inbreeding on disease susceptibility. Extremely inbred populations of Galápagos hawks had higher parasite abundances than relatively outbred populations. We found a significant island effect on constitutively produced natural antibody (NAb) levels and inbred populations generally harboured lower average and less variable NAb levels than relatively outbred populations. Furthermore, NAb levels explained abundance of amblyceran lice, which encounter the host immune system. This is the first study linking inbreeding, innate immunity and parasite load in an endemic, in situ wildlife population and provides a clear framework for assessment of disease risk in a Galápagos endemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.