Trial reportInternational wound journal2005
The effect of a silver-containing Hydrofiber dressing on superficial wound bed and bacterial balance of chronic wounds.
Trial report in International wound journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Antibiotics and antiseptics for venous leg ulcers.The Cochrane database of systematic reviews · 2014Pooled it
- Prevention of hypergranulation tissue after gastrostomy tube placement: A randomised controlled trial of hydrocolloid dressings.International wound journal · 2019Trial
- A prospective, multi-centre, randomised, open label, parallel, comparative study to evaluate effects of AQUACEL® Ag and Urgotul® Silver dressing on healing of chronic venous leg ulcers.International wound journal · 2012Trial
- Knee dressing selection and infection rates in primary total knee arthroplasty: a single-center retrospective review.Annals of joint · 2026Article
- Skin Protection With Hydrofibre Foam and Silicone-Based Dressing Can Help Prevent Pressure Injuries: A Preliminary Evaluation in Brazil.International wound journal · 2025Article
- Electrochemical Devices in Cutaneous Wound Healing.Bioengineering (Basel, Switzerland) · 2023Review
- Article
- Chronic Leg Ulcers: Are Tissue Engineering and Biomaterials Science the Solution?Bioengineering (Basel, Switzerland) · 2021Review
- Nanosilver-Silica Composite: Prolonged Antibacterial Effects and Bacterial Interaction Mechanisms for Wound Dressings.Nanomaterials (Basel, Switzerland) · 2017Article
- Multidrug-resistant organisms, wounds and topical antimicrobial protection.International wound journal · 2012Article
- AQUACEL® Ag Dressing with Hydrofiber® Technology.Advances in wound care · 2012Article
- Microcrystalline cellulose membrane for re-epithelisation of chronic leg wounds: a prospective open study.International wound journal · 2010Article
- A review of the applications of the hydrofiber dressing with silver (Aquacel Ag) in wound care.Therapeutics and clinical risk management · 2010Article
- The increasing problem of wound bacterial burden and infection in acute and chronic soft-tissue wounds caused by methicillin-resistant Staphylococcus aureus.Journal of burns and wounds · 2007Article
- Wound bed preparation and oxygen balance--a new component?International wound journal · 2007Article
- The effect of multifunctional polymer-based gels on wound healing in full thickness bacteria-contaminated mouse skin wound models.Biomaterials · 2007Article
- Review
- Silver dressings: their role in wound management.International wound journal · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of chronic wounds represents a major cost to society and has a profound effect on the participant's quality of life. Chronic wounds may have an increased bacterial burden that can impair healing without all the clinical signs of infection. Silver dressings may provide an alternative topical method to control bacterial burden. The primary aim of this study was to evaluate the clinical improvement in chronic wounds through the effect on wound size, maceration, resolution of surface slough and conversion to healthy granulation during a 4-week application of the silver-containing Hydrofiber dressing. This was a single centre, open-label case series study which included a total of 30 evaluable participants: four with diabetic neuropathic foot ulcers, 13 venous stasis ulcers, four pressure ulcers and nine miscellaneous wounds that did not fit any of the previous categories. All participants had adequate vascular supply, indicating the potential to heal. The wounds were stalled or had the signs and symptoms consistent with critical colonisation. The underlying cause of the ulceration was identified and corrected, or the symptoms and signs were treated. This was followed by the application of silver-containing Hydrofiber dressings for a period of 4 weeks. The majority of wounds treated decreased in size (70%) with decreased exudate, decreased purulence and resolution of surface slough (75%). There was an increased quality and quantity of healthy granulation tissue. Unlike some silver dressings, the Hydrofiber and silver combination dressing was unlikely to cause burning and stinging on application. Peri-wound maceration was present in 54% of participants at baseline, and 85% of these resolved with this dressing. A desloughing action was seen in those patients with pre-existing slough at baseline and its removal will lower the bacterial burden of the wound.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.