Evidence map›Paper›PMID 16617413›Full record

ArticleJournal of materials science. Materials in medicine2006

Design of gelatin nanoparticles as swelling controlled delivery system for chloroquine phosphate.

A K Bajpai, Jyoti Choubey

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 156 citations in OpenAlex.

  1. Review
  2. Review
  3. Effect of hydroxychloroquine sulfate on the gelation behavior, water mobility and structure of gelatin.Colloids and surfaces. A, Physicochemical and engineering aspects · 2022
    Article
  4. Repurpose but also (nano)-reformulate! The potential role of nanomedicine in the battle against SARS-CoV2.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Nano-biotechnology: a new approach to treat and prevent malaria.International journal of nanomedicine · 2019
    Review
  11. Protein Polymer-Based Nanoparticles: Fabrication and Medical Applications.International journal of molecular sciences · 2018
    Review
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A K BajpaiBose Memorial Research Laboratory, Department of Chemistry, Government Autonomous Science College, Jabalpur, M.P. 482001, India. akbmrl@yahoo.co.in
Jyoti Choubey
Bose (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gelatin nanoparticles were prepared by a single W/O emulsion technique and characterized by infrared (IR) spectra, scanning electron microscopy (SEM) and particle size analysis. The prepared nanoparticles were loaded with chloroquine phosphate (CP), a well known antimalarial drug, and the release dynamics of entrapped drug was investigated as a function of various experimental factors such as percent loading of the drug, chemical architecture of the nanocarriers, and pH, temperature, ionic strength and nature of the release medium. The nanoparticles were also studied for their water sorption capacity by optical microscopic method taking advantage of the aggregation of nanoparticles. The drug release processes was analyzed kinetically using Ficks power law and a correlation was established between the quantity of released drug and swelling of the nanoparticles.

Indexed as

AbsorptionChloroquineDelayed-Action PreparationsDiffusionDrug StabilityGelatinKineticsMolecular ConformationNanostructuresParticle SizeChloroquinechloroquine diphosphateDelayed-Action PreparationsGelatin

Identifiers

PMID16617413
OpenAlexW1991560774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.