ArticleLeukemia2006
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent.
Article in Leukemia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- MLL-Rearranged Acute Lymphoblastic Leukemia.Current hematologic malignancy reports · 2020Review
- The genomics of acute myeloid leukemia in children.Cancer metastasis reviews · 2020Review
- AURKA Suppresses Leukemic THP-1 Cell Differentiation through Inhibition of the KDM6B Pathway.Molecules and cells · 2018Article
- MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Frontiers in pediatrics · 2017Review
- Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia.Oncotarget · 2016Article
- Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy.Leukemia · 2014Article
- Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy.Nature · 2012Article
- Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia.PloS one · 2011Article
- The role of HDACs inhibitors in childhood and adolescence acute leukemias.Journal of biomedicine & biotechnology · 2011Review
- Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.Investigational new drugs · 2010Review
- In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase.Molecular imaging and biology · 2010Article
- Therapeutic targeting of MLL.Blood · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.