ReviewDigestive diseases and sciences2006
Sandifer syndrome posturing: relation to abdominal wall contractions, gastroesophageal reflux, and fundoplication.
Review in Digestive diseases and sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- A systematic review of Sandifer syndrome in children with severe gastroesophageal reflux.Pediatric surgery international · 2024Pooled it
- Paroxysmal head drops with ataxia-like symptoms presenting as Sandifer syndrome in a 3-year old girl.BMJ case reports · 2020Article
- Diagnosis and management of Sandifer syndrome in children with intractable neurological symptoms.European journal of pediatrics · 2020Review
- A chronic case of adult-onset Sandifer syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013Article
- Surgical management of pediatric gastroesophageal reflux disease.Gastroenterology research and practice · 2013Article
- Prevalence and characteristics of abnormal head posture in children with Down syndrome: a 20-year retrospective, descriptive review.Ophthalmology · 2011Article
- THE LINDA CRANE MEMORIAL LECTURE: The Patient Puzzle: Piecing it Together.Cardiopulmonary physical therapy journal · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sandifer syndrome designates abnormal posturing in patients with gastroesophageal reflux. To explore its mechanisms via examining relationships among Sandifer syndrome posturing, abdominal wall contractions, and reflux episodes, we studied an affected child in detail. The study utilized esophageal pHmetry, surface electromyography, and split-screen videography. The multichannel physiologic study demonstrated association of rectus abdominis contraction with onset of reflux episodes (P < 0.001) and association of reflux episodes with Sandifer syndrome posturing. This child's subsequent course confirmed his diagnosis and suggested mechanisms of the association of reflux and Sandifer syndrome. We conclude that abdominal wall contractions may induce reflux episodes. Sandifer syndrome may be due to gastroesophageal reflux even without hiatal hernia, macroscopic esophagitis, or reflux symptoms. Despite the absence of more typical reflux symptoms and failure to respond to very aggressive medical therapy, Sandifer syndrome may resolve after fundoplication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.