ReviewJournal of autism and developmental disorders2006
Hyperserotoninemia and altered immunity in autism.
Review in Journal of autism and developmental disorders, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Immune Dysregulation in Autism Spectrum Disorder: What Do We Know about It?International journal of molecular sciences · 2022Review
- Biomarker study of the biological parameter and neurotransmitter levels in autistics.Molecular and cellular biochemistry · 2020Article
- Studies on regeneration of central nervous system and social ability of the earthworm Eudrilus eugeniae.Invertebrate neuroscience : IN · 2016Article
- Investigation of signaling molecules and metabolites found in crustacean hemolymph via in vivo microdialysis using a multifaceted mass spectrometric platform.Electrophoresis · 2016Article
- Biomarkers in autism.Frontiers in psychiatry · 2014Review
- Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene.Molecular autism · 2014Article
- A review of the serotonin transporter and prenatal cortisol in the development of autism spectrum disorders.Molecular autism · 2013Article
- Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.Frontiers in molecular neuroscience · 2013Article
- Low serum IgA and increased expression of CD23 on B lymphocytes in peripheral blood in children with regressive autism aged 3-6 years old.Archives of medical science : AMS · 2012Article
- The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis.Journal of chemical neuroanatomy · 2011Review
- A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic children.Journal of neuroinflammation · 2011Article
- Pleiotropic effects of neurotransmission during development: modulators of modularity.Journal of autism and developmental disorders · 2009Review
- Article
- Brief report: normal intestinal permeability at elevated platelet serotonin levels in a subgroup of children with pervasive developmental disorders in Curaçao (The Netherlands antilles).Journal of autism and developmental disorders · 2008Article
- The neurobiology of autism.Brain pathology (Zurich, Switzerland) · 2007Review
- Atypical antipsychotics in children with pervasive developmental disorders.Paediatric drugs · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most consistent biological findings in autism is elevated whole blood serotonin (5-HT) levels found in about 1/3 of cases. Immune abnormalities are also commonly observed in this disorder. Given 5-HT's role as an immunomodulator, possible connections between 5-HT and immune abnormalities in autism are explored in this review. Areas of focus include hyperserotoninemia and cellular immune function, autoantibodies to 5-HT receptors, and 5-HT's role in autoimmunity. Further research is needed to determine the interactions between neuropsychiatric and immune dysfunction in autism and related disorders.
Indexed as
Identifiers
16614791What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.