ArticleMolecular genetics and genomics : MGG2006
Testifying the rice bacterial blight resistance gene xa5 by genetic complementation and further analyzing xa5 (Xa5) in comparison with its homolog TFIIAgamma1.
Article in Molecular genetics and genomics : MGG, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 139 citations in OpenAlex.
- The Rice-Xoc Arms Race: Molecular Mechanisms and Genomic Strategies Against Bacterial Leaf Streak.Rice (New York, N.Y.) · 2026Review
- Population-scale multi-omics analysis reveals diverse phenotypic impacts of lncRNAs in rice.Cell research · 2026Article
- Effector Triggered Susceptibility and Immunity in Bacterial Diseases of Leaf Blight and Streak in Rice.Rice (New York, N.Y.) · 2026Review
- Resistance gene againstFrontiers in plant science · 2026Review
- Recent Progress in Rice-Biology · 2025Review
- Genetic engineering, including genome editing, for enhancing broad-spectrum disease resistance in crops.Plant communications · 2025Review
- The Roles of MicroRNAs in the Regulation of Rice-Pathogen Interactions.Plants (Basel, Switzerland) · 2025Review
- Recent advances in innovative strategies for plant disease resistance breeding.Frontiers in plant science · 2025Review
- The general transcription factors (GTFs) of RNA polymerase II and their roles in plant development and stress responses.Critical reviews in biochemistry and molecular biology · 2024Review
- Genome-Wide Association Studies and QTL Mapping Reveal a New Locus Associated with Resistance to Bacterial Pustule Caused byPlants (Basel, Switzerland) · 2024Article
- Genome-wide analyses of LATERAL ORGAN BOUNDARIES in cassava reveal the role of LBD47 in defence against bacterial blight.PloS one · 2023Article
- TALEs as double-edged swords in plant-pathogen interactions: Progress, challenges, and perspectives.Plant communications · 2022Review
- Plant Executor Genes.International journal of molecular sciences · 2022Review
- Research Progress on Cloning and Function ofFrontiers in plant science · 2022Review
- A new NLR disease resistance geneFrontiers in plant science · 2022Article
- Recent Progress in Rice Broad-Spectrum Disease Resistance.International journal of molecular sciences · 2021Review
- Genome-Wide Association Study of QTLs Conferring Resistance to Bacterial Leaf Streak in Rice.Plants (Basel, Switzerland) · 2021Article
- SWEET genes and TAL effectors for disease resistance in plants: Present status and future prospects.Molecular plant pathology · 2021Review
- Genome-wide association study and transcriptome analysis discover new genes for bacterial leaf blight resistance in rice (Oryza sativa L.).BMC plant biology · 2021Article
- Xa7, a Small Orphan Gene Harboring Promoter Trap for AvrXa7, Leads to the Durable Resistance to Xanthomonas oryzae Pv. oryzae.Rice (New York, N.Y.) · 2021Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recessive gene xa5 for resistance to bacterial blight resistance of rice is located on chromosome 5, and evidence based on genetic recombination has been shown to encode a small subunit of the basal transcription factor IIA (Iyer and McCouch in MPMI 17(12):1348-1354, 2004). However, xa5 has not been demonstrated by a complementation test. In this study, we introduced the dominant allele Xa5 into a homozygous xa5-line, which was developed from a cross between IRBB5 (an indica variety with xa5) and Nipponbare (a japonica variety with Xa5). Transformation of Xa5 and subsequent segregation analysis confirmed that xa5 is a V39E substitution variant of the gene for TFIIAgamma on chromosome 5 (TFIIAgamma5 or Xa5). The rice has an addition gene for TFIIAgamma exists on chromosome 1 (TFIIAgamma1). Analysis of the expression patterns of Xa5 (TFIIAgamma5)/xa5 and TFIIAgamma1 revealed that both the genes are constitutively expressed in different rice organs. However, no expression of TFIIAgamma1 could be detected in the panicle by reverse transcriptase-polymerase chain reaction. To compare the structural difference between the Xa5/xa5 and TFIIAgamma1 proteins, 3-D structures were predicted using computer-aided modeling techniques. The modeled structures of Xa5 (xa5) and TFIIAgamma1 fit well with the structure of TFIIA small subunit from human, suggesting that they may all act as a small subunit of TFIIA. The E39V substitution in the xa5 protein occurs in the alpha-helix domain, a supposed conservative substitutable site, which should not affect the basal transcription function of TFIIAgamma. The structural analysis indicates that xa5 and Xa5 potentially retain their basic transcription factor function, which, in turn, may mediate the novel pathway for bacterial blight resistance and susceptibility, respectively.
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