Evidence map›Paper›PMID 16614249›Full record

ReviewClinical microbiology reviews2006

Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy.

Barbara A Brown-Elliott, June M Brown, Patricia S Conville, Richard J Wallace

Abstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 497 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
497citing papers in PubMed, 3 pooled it
39.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

497 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,092 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Clinical Characteristics and Treatment Outcome of Central Nervous System Nocardiosis: A Systematic Review of Reported Cases.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Pooled it
  4. Article
  5. Article
  6. Nocardiosis: death from the ground.Journal of medicine and life · 2026
    Article
  7. Article
  8. Article
  9. Article
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  11. First Report ofAnimals : an open access journal from MDPI · 2026
    Article
  12. Synergistic and additive in vitro interactions of imipenem, trimethoprim-sulfamethoxazole, amikacin, and clofazimine against clinical isolates of Nocardia wallacei.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  13. Article
  14. Isolation, Identification and Whole-Genome Sequencing of aAnimals : an open access journal from MDPI · 2026
    Article
  15. Article
  16. SinonasalThe Canadian veterinary journal = La revue veterinaire canadienne · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

437 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Barbara A Brown-ElliottDepartment of Microbiology, The University of Texas Health Center, 11937 U.S. Highway 271, Tyler, 75708, USA.
June M Brown
Patricia S Conville
Richard J Wallace
Centers for Disease Control and Prevention · USNational Institutes of Health · USThe University of Texas Health Science Center at Tyler · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent explosion of newly described species of Nocardia results from the impact in the last decade of newer molecular technology, including PCR restriction enzyme analysis and 16S rRNA sequencing. These molecular techniques have revolutionized the identification of the nocardiae by providing rapid and accurate identification of recognized nocardiae and, at the same time, revealing new species and a number of yet-to-be-described species. There are currently more than 30 species of nocardiae of human clinical significance, with the majority of isolates being N. nova complex, N. abscessus, N. transvalensis complex, N. farcinica, N. asteroides type VI (N. cyriacigeorgica), and N. brasiliensis. These species cause a wide variety of diseases and have variable drug susceptibilities. Accurate identification often requires referral to a reference laboratory with molecular capabilities, as many newer species are genetically distinct from established species yet have few or no distinguishing phenotypic characteristics. Correct identification is important in deciding the clinical relevance of a species and in the clinical management and treatment of patients with nocardial disease. This review characterizes the currently known pathogenic species of Nocardia, including clinical disease, drug susceptibility, and methods of identification.

Indexed as

Anti-Bacterial AgentsBacteriological TechniquesCulture MediaDNA, BacterialHumansLung DiseasesMicrobial Sensitivity TestsNocardiaNocardia InfectionsPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthRNA, BacterialRNA, Ribosomal, 16SSkin DiseasesSpecies SpecificityAnti-Bacterial AgentsCulture MediaDNA, BacterialRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID16614249
PMCPMC1471991
OpenAlexW2129706499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.