ArticleThe Biochemical journal2006
Identification of a nuclear-localized nuclease from wheat cells undergoing programmed cell death that is able to trigger DNA fragmentation and apoptotic morphology on nuclei from human cells.
Article in The Biochemical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 62 citations in OpenAlex.
- Biological Functions of Hydrogen Sulfide in Plants.International journal of molecular sciences · 2022Review
- A NAC-EXPANSIN module enhances maize kernel size by controlling nucellus elimination.Nature communications · 2022Article
- Article
- ZnCells · 2021Article
- Gene Mapping, Genome-Wide Transcriptome Analysis, and WGCNA Reveals the Molecular Mechanism for Triggering Programmed Cell Death in Rice MutantPlants (Basel, Switzerland) · 2020Article
- Ca2+-dependent nuclease is involved in DNA degradation during the formation of the secretory cavity by programmed cell death in fruit of Citrus grandis 'Tomentosa'.Journal of experimental botany · 2020Article
- Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay ofMolecules (Basel, Switzerland) · 2020Article
- Transcriptomic profiling identifies differentially expressed genes associated with programmed cell death of nucellar cells in Ginkgo biloba L.BMC plant biology · 2019Article
- Deterioration of willow seeds during storage.Scientific reports · 2018Article
- Caffeine-Induced Premature Chromosome Condensation Results in the Apoptosis-Like Programmed Cell Death in Root Meristems of Vicia faba.PloS one · 2015Article
- The crucial elements of the 'last step' of programmed cell death induced by kinetin in root cortex of V. faba ssp. minor seedlings.Plant cell reports · 2014Article
- The pathogenesis-related protein PR-4b from Theobroma cacao presents RNase activity, Ca(2+) and Mg(2+) dependent-DNase activity and antifungal action on Moniliophthora perniciosa.BMC plant biology · 2014Article
- Programmed cell death (PCD): an essential process of cereal seed development and germination.Frontiers in plant science · 2014Review
- Identification of a type I Ca2+/Mg2+-dependent endonuclease induced in maize cells exposed to camptothecin.BMC plant biology · 2013Article
- Ricinosomes provide an early indicator of suspensor and endosperm cells destined to die during late seed development in quinoa (Chenopodium quinoa).Annals of botany · 2013Article
- Programmed cell death during quinoa perisperm development.Journal of experimental botany · 2013Article
- The scutellum of germinated wheat grains undergoes programmed cell death: identification of an acidic nuclease involved in nucleus dismantling.Journal of experimental botany · 2012Article
- Family life at close quarters: communication and constraint in angiosperm seed development.Protoplasma · 2010Review
- Formation of archegonium chamber is associated with nucellar-cell programmed cell death in Ginkgo biloba.Protoplasma · 2007Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PCD (programmed cell death) in plants presents important morphological and biochemical differences compared with apoptosis in animal cells. This raises the question of whether PCD arose independently or from a common ancestor in plants and animals. In the present study we describe a cell-free system, using wheat grain nucellar cells undergoing PCD, to analyse nucleus dismantling, the final stage of PCD. We have identified a Ca2+/Mg2+ nuclease and a serine protease localized to the nucleus of dying nucellar cells. Nuclear extracts from nucellar cells undergoing PCD triggered DNA fragmentation and other apoptotic morphology in nuclei from different plant tissues. Inhibition of the serine protease did not affect DNA laddering. Furthermore, we show that the nuclear extracts from plant cells triggered DNA fragmentation and apoptotic morphology in nuclei from human cells. The inhibition of the nucleolytic activity with Zn2+ or EDTA blocked the morphological changes of the nucleus. Moreover, nuclear extracts from apoptotic human cells triggered DNA fragmentation and apoptotic morphology in nuclei from plant cells. These results show that degradation of the nucleus is morphologically and biochemically similar in plant and animal cells. The implication of this finding on the origin of PCD in plants and animals is discussed.
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