ArticleDiabetologia2006
Anaemia in diabetic patients with chronic kidney disease--prevalence and predictors.
Article in Diabetologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Risk Factors for Anemia in Patients with Chronic Renal Failure: A Systematic Review and Meta-Analysis.Ethiopian journal of health sciences · 2020Pooled it
- Plasma Erythropoietin Levels and Anemia in Vietnamese Patients With Type 2 Diabetes and Chronic Kidney Disease: 2018-2019.Health science reports · 2026Article
- Risk factors for persistent decline in eGFR of Japanese patients with diabetes: Analysis using a large-scale diabetes registry J-DREAMS.Journal of diabetes investigation · 2026Article
- A Narrative Review of Stem Cell-Derived Exosomes for Diabetic Nephropathy.Stem cells international · 2026Review
- Use of SGLT2 Inhibitors vs GLP-1 RAs and Anemia in Patients With Diabetes and CKD.JAMA network open · 2024Article
- Peripheral Cytopenia and Its Associated Factors in Type 2 Diabetes Mellitus Patients, Northwest Ethiopia.Journal of blood medicine · 2022Article
- Treatment of anemia in difficult-to-manage patients with chronic kidney disease.Kidney international supplements · 2021Article
- Magnitude and factors associated with anemia among diabetic patients in Ethiopia: A systematic review and meta-analysis.SAGE open medicine · 2021Article
- Article
- Ethnic prevalence of anemia and predictors of anemia among chronic kidney disease patients at a tertiary hospital in Johannesburg, South Africa.International journal of nephrology and renovascular disease · 2019Article
- Article
- Anemia modifies the prognostic value of glycated hemoglobin in patients with diabetic chronic kidney disease.PloS one · 2018Article
- Diabetes mellitus increases the prevalence of anemia in patients with chronic kidney disease: A nested case-control study.World journal of nephrology · 2016Article
- Predictors of anemia in a multi-ethnic chronic kidney disease population: a case-control study.SpringerPlus · 2015Article
- Urinary liver-type fatty acid-binding protein and progression of diabetic nephropathy in type 1 diabetes.Diabetes care · 2013Article
- Association of anemia and renal function test among diabetes mellitus patients attending Fenote Selam Hospital, West Gojam, Northwest Ethiopia: a cross sectional study.BMC hematology · 2013Article
- Low hemoglobin concentration is associated with several diabetic profiles.The Korean journal of internal medicine · 2012Article
- Mild anemia is frequent and associated with micro- and macroangiopathies in patients with type 2 diabetes mellitus.Journal of diabetes investigation · 2010Article
- Correlates of anemia in American blacks and whites: the REGARDS Renal Ancillary Study.American journal of epidemiology · 2009Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
aims/hypothesisWe investigated the relationship between haemoglobin (Hb) and diabetes in patients with renal disease. SUBJECTS, MATERIALS AND
methodsAll adult patients with stable chronic kidney disease attending renal or diabetic outpatient clinics in a six-month period were identified. Patients' notes and electronic patient records were used to build a comprehensive biochemical and clinical database. Results were analysed for the predictors of Hb, the severity of anaemia in both groups and the relative impact of diabetes on haemoglobin and anaemia.
resultsThe study group consisted of 468 patients, of whom 204 had diabetes and 264 did not. At every level of renal function haemoglobin levels were lower by an average of 10 g/l in subjects with diabetes than in those without. Likewise, anaemia was found to occur at an earlier stage of chronic kidney disease (and to be of greater severity) in diabetic patients. Independent predictors of haemoglobin included female sex, diabetes, renal function and serum albumin, with diabetes and renal function being the greatest predictors. Multiple logistic regression showed that patients with diabetes had an odds ratio of 4 for being anaemic. Had we used an estimated GFR of less than 60 ml/min to trigger investigation of anaemia, we would have detected 85% of anaemic patients. CONCLUSIONS/
interpretationAnaemia is frequently found in diabetic patients with renal disease, occurs earlier and is more severe than in similar but non-diabetic subjects. In contrast to previous publications, our findings suggest that anaemia is prevalent at the earliest stages of chronic kidney disease. We advocate an estimated GFR threshold of <60 ml/min to trigger investigation for anaemia in diabetic subjects.
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