Evidence map›Paper›PMID 16608666›Full record

ReviewCurrent HIV/AIDS reports2006

New antiretroviral drugs.

Kimberly Hanson, Charles Hicks

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kimberly HansonDuke University Medical Center, Division of Infectious Diseases and International Health, Box 3879, Durham, NC 27710, USA. kim.hanson@duke.edu
Charles Hicks

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the availability of 21 antiretroviral drugs approved for the treatment of HIV infection, current combination regimens remain hampered by issues of toxicity, convenience, cost, incomplete viral suppression, and drug resistance. Expansion of the currently available therapeutic options through the reformulation of available agents, discovery of new compounds with antiretroviral activity, and the exploitation of novel drug targets are critical. This review describes the status of new nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, and fusion inhibitors. We also summarize new classes of antiretroviral therapy in clinical development including the attachment inhibitors, chemokine receptor antagonists, integrase inhibitors, and maturation inhibitors.

Indexed as

Anti-HIV AgentsDrug DesignDrug Therapy, CombinationHIV-1HIV Fusion InhibitorsHIV InfectionsHIV Integrase InhibitorsHIV Protease InhibitorsHumansReceptors, ChemokineReverse Transcriptase InhibitorsAnti-HIV AgentsHIV Fusion InhibitorsHIV Integrase InhibitorsHIV Protease InhibitorsReceptors, ChemokineReverse Transcriptase Inhibitors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.