Evidence map›Paper›PMID 16608311›Full record

ArticleJournal of the American Chemical Society2006

Enantioselective total synthesis of bistramide A.

Michael T Crimmins, Amy C DeBaillie

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Asymmetric synthesis of naturally occurring spiroketals.Molecules (Basel, Switzerland) · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael T CrimminsDepartment of Chemistry, Venable and Kenan Laboratories of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA. crimmins@email.unc.edu
Amy C DeBaillie

Funding

SYNTHESIS OF CYCLOPENTANOIDS BY PHOTOCYCLOADDITONSR01GM038904 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CRIMMINS, MICHAEL T. · 1987 to 2006
$1.6M
ASYMMETRIC SYNTHESIS OF ANTITUMOR POLYKETIDESR01CA063572 · NCI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CRIMMINS, MICHAEL T. · 1995 to 2005
$1.6M
NCI NIH HHS CA63572NCI NIH HHS R01 CA063572NIGMS NIH HHS R01 GM038904
6 · The paper itself

Abstract

The enantioselective synthesis of bistramide A has been achieved with a longest linear sequence of 18 steps. The synthetic strategy involves the use of a distereoselective glycolate alkylation, an aldol addition of a chlorotitanium enolate of N-acylthiazolidinthione, and a Sharpless asymmetric epoxidation to synthesize the three key fragments.

Indexed as

AcetamidesAnimalsPyransSpiro CompoundsStereoisomerismUrochordataAcetamidesbistratene APyransSpiro Compounds

Identifiers

PMID16608311
PMCPMC2546575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.