ReviewCytometry. Part A : the journal of the International Society for Analytical Cytology2006
Multiplexed and microparticle-based analyses: quantitative tools for the large-scale analysis of biological systems.
Review in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 119 citations in OpenAlex.
- Flow Cytometry Multiplex Bead Array Technology and Its Immunological Clinical Applications in Covid-19 Era.Balkan journal of medical genetics : BJMG · 2025Article
- Toward predictive engineering of gene circuits.Trends in biotechnology · 2023Review
- Monoplex and multiplex immunoassays: approval, advancements, and alternatives.Comparative clinical pathology · 2022Review
- Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays.Analytical chemistry · 2021Article
- Spectral-Time Multiplexing in FRET Complexes of AgInSNanomaterials (Basel, Switzerland) · 2020Article
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).European journal of immunology · 2019Article
- Ultrasimple Single-Cell Detection of Multiple Cytokines by a Nanowell Chip Integrated with Encoded Microarrays.ACS sensors · 2019Article
- An open-source software analysis package for Microspheres with Ratiometric Barcode Lanthanide Encoding (MRBLEs).PloS one · 2019Article
- Early diagnosis of disease using microbead array technology: A review.Analytica chimica acta · 2018Review
- Multiphoton-Polymerized 3D Protein Assay.ACS applied materials & interfaces · 2018Article
- Cytokine-based Predictive Models to Estimate the Probability of Chronic Periodontitis: Development of Diagnostic Nomograms.Scientific reports · 2017Article
- A Microsphere-Supported Lipid Bilayer Platform for DNA Reactions on a Fluid Surface.ACS applied materials & interfaces · 2017Article
- Article
- Programmable Microfluidic Synthesis of Over One Thousand Uniquely Identifiable Spectral Codes.Advanced optical materials · 2017Article
- Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection.PloS one · 2017Article
- Transport of biomolecules to binding partners displayed on the surface of microbeads arrayed in traps in a microfluidic cell.Biomicrofluidics · 2017Article
- High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.Molecular & cellular proteomics : MCP · 2016Article
- ELISA in the multiplex era: potentials and pitfalls.Proteomics. Clinical applications · 2015Review
- Spectral flow cytometry.Current protocols in cytometry · 2013Review
- Single cell analysis using surface enhanced Raman scattering (SERS) tags.Methods (San Diego, Calif.) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
While the term flow cytometry refers to the measurement of cells, the approach of making sensitive multiparameter optical measurements in a flowing sample stream is a very general analytical approach. The past few years have seen an explosion in the application of flow cytometry technology for molecular analysis and measurements using microparticles as solid supports. While microsphere-based molecular analyses using flow cytometry date back three decades, the need for highly parallel quantitative molecular measurements that has arisen from various genomic and proteomic advances has driven the development in particle encoding technology to enable highly multiplexed assays. Multiplexed particle-based immunoassays are now common place, and new assays to study genes, protein function, and molecular assembly. Numerous efforts are underway to extend the multiplexing capabilities of microparticle-based assays through new approaches to particle encoding and analyte reporting. The impact of these developments will be seen in the basic research and clinical laboratories, as well as in drug development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.