Evidence map›Paper›PMID 16603624›Full record

ArticleClinical and vaccine immunology : CVI2006

ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy.

Fabrizio Vitale, Stefano Reale, Enrico Petrotta, Santo Caracappa, Annalisa Barera, Marco Pio La Manna, Pasquale Macaluso, Nadia Caccamo, Francesco Dieli, Hans Martin Vordermeier and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Fabrizio VitaleIstituto Zooprofilattico Sperimentale della Sicilia, Via G. Marinuzzi 3, 90100 Palermo, Italia.
Stefano Reale
Enrico Petrotta
Santo Caracappa
Annalisa Barera
Marco Pio La Manna
Pasquale Macaluso
Nadia Caccamo
Francesco Dieli
Hans Martin Vordermeier
Guido Sireci
Alfredo Salerno
University of Palermo · ITVeterinary Medicines Directorate · GBIstituto Zooprofilattico Sperimentale Della Sicilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.

Indexed as

Amino Acid SequenceAnimalsAntigens, BacterialBacterial ProteinsCattleCD8-Positive T-LymphocytesCells, CulturedEpitopes, T-LymphocyteFemaleInterferon-gammaLymphocyte ActivationMiceMolecular Sequence DataMycobacterium bovisSicilyTuberculosis, BovineAntigens, BacterialBacterial ProteinsEpitopes, T-LymphocyteESAT-6 protein, Mycobacterium tuberculosisInterferon-gamma

Identifiers

PMID16603624
PMCPMC1459644
OpenAlexW2104163972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.