ArticleBiophysical journal2006
Clustering of cyclic-nucleotide-gated channels in olfactory cilia.
Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 60 citations in OpenAlex.
- Constancy of olfactory cilia in rodents.Chemical senses · 2025Article
- Olfactory cilia, regulation and control of olfaction.Physiological reports · 2024Review
- The cyclic AMP signaling pathway in the rodent main olfactory system.Cell and tissue research · 2021Review
- Maturation of the Olfactory Sensory Neuron and Its Cilia.Chemical senses · 2020Review
- Therapeutic perspectives for structural and functional abnormalities of cilia.Cellular and molecular life sciences : CMLS · 2019Review
- Antagonism in olfactory receptor neurons and its implications for the perception of odor mixtures.eLife · 2018Article
- The long tale of the calcium activated ClChannels (Austin, Tex.) · 2017Review
- Spontaneously active NaV1.5 sodium channels may underlie odor sensitivity.Journal of neurophysiology · 2016Article
- Review
- Electrical Signaling in Motile and Primary Cilia.Bioscience · 2014Article
- Compartments within a compartment: what C. elegans can tell us about ciliary subdomain composition, biogenesis, function, and disease.Organogenesis · 2014Review
- Primary cilia and dendritic spines: different but similar signaling compartments.Molecules and cells · 2013Review
- Cell- and subunit-specific mechanisms of CNG channel ciliary trafficking and localization in C. elegans.Journal of cell science · 2013Article
- Analysis of KIF17 distal tip trafficking in zebrafish cone photoreceptors.Vision research · 2012Article
- The future of ciliary and flagellar membrane research.Molecular biology of the cell · 2012Article
- The kinesin superfamily protein KIF17: one protein with many functions.Biomolecular concepts · 2012Article
- Perspectives on: information and coding in mammalian sensory physiology: response kinetics of olfactory receptor neurons and the implications in olfactory coding.The Journal of general physiology · 2011Article
- Article
- Signaling by olfactory receptor neurons near threshold.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Specificities of olfactory receptor neuron responses to amino acids in the black bullhead catfish (Ameiurus melas).Pflugers Archiv : European journal of physiology · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Olfactory cilia contain the known components of olfactory signal transduction, including a high density of cyclic-nucleotide-gated (CNG) channels. CNG channels play an important role in mediating odor detection. The channels are activated by cAMP, which is formed by a G-protein-coupled transduction cascade. Frog olfactory cilia are 25-200 microm in length, so the spatial distribution of CNG channels along the length should be important in determining the sensitivity of odor detection. We have recorded from excised cilia and modeled diffusion of cAMP into a cilium to determine the spatial distribution of the CNG channels along the ciliary length. The proximal segment, which in frog is the first 20% of the cilium, appears to express a small fraction of the CNG channels, whereas the distal segment contains the majority, mostly clustered in one region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.