ReviewFrontiers in neuroendocrinology2006
Hippocampal neuroplasticity induced by early-life stress: functional and molecular aspects.
Review in Frontiers in neuroendocrinology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
What it found
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Who cites it
93 citing papers in PubMed.
- Subcortical brain abnormalities and cognitive function in individuals with psychosis and their unaffected relatives: A normative modeling approach.Schizophrenia research · 2025Article
- Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.Pain · 2025Article
- The evolving neurobiology of early-life stress.Neuron · 2025Review
- Correlation of screen exposure to stress, learning, cognitive and language performance in children.European child & adolescent psychiatry · 2025Article
- Annual Research Review: Exposure to environmental chemicals and psychosocial stress and the development of children's learning difficulties.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Left OFC Activation in Functional Near-Infrared Spectroscopy during an Inhibitory Control Task in an Early Years Sample: Integrating Stress Responses with Cognitive Function and Brain Activation.Developmental neuroscience · 2025Article
- Cognitive enrichment improves spatial memory and alters hippocampal synaptic connectivity in a mouse model for early-life stress.Frontiers in cellular neuroscience · 2025Article
- Socioeconomic status moderates associations between hippocampal development and cognition in preterms.Annals of clinical and translational neurology · 2024Article
- Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries.Physiological reviews · 2024Review
- The effects of early-life and intergenerational stress on the brain.Proceedings. Biological sciences · 2023Article
- Hypothalamus and Post-Traumatic Stress Disorder: A Review.Brain sciences · 2023Review
- Maternal adverse childhood experiences and infant subcortical brain volume.Neurobiology of stress · 2022Article
- Corticotropin releasing factor neurons in the visual cortex mediate long-term changes in visual function induced by early adversity.Neurobiology of stress · 2022Article
- Development of Spatial Orientation in Two-to-Three-Year-Old Children in Relation to Lifestyle Factors.Nutrients · 2022Article
- Understanding how stress responses and stress-related behaviors have evolved in zebrafish and mammals.Neurobiology of stress · 2021Article
- Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System.International journal of molecular sciences · 2021Review
- The Contribution of Epigenetic Inheritance Processes on Age-Related Cognitive Decline and Alzheimer's Disease.Epigenomes · 2021Review
- Chemical Stimulation of Rodent and Human Cortical Synaptosomes: Implications in Neurodegeneration.Cells · 2021Article
- Stress hormones mediate developmental plasticity in vertebrates with complex life cycles.Neurobiology of stress · 2021Article
- Proteomic and mitochondrial adaptations to early-life stress are distinct in juveniles and adults.Neurobiology of stress · 2020Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Whereas genetic factors contribute crucially to brain function, early-life events, including stress, exert long-lasting influence on neuronal function. Here, we focus on the hippocampus as the target of these early-life events because of its crucial role in learning and memory. Using a novel immature-rodent model, we describe the deleterious consequences of chronic early-life 'psychological' stress on hippocampus-dependent cognitive tasks. We review the cellular mechanisms involved and discuss the roles of stress-mediating molecules, including corticotropin releasing hormone, in the process by which stress impacts the structure and function of hippocampal neurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.