Evidence map›Paper›PMID 16599646›Full record

ReviewCNS drugs2006

Tailoring nicotine replacement therapy: rationale and potential approaches.

Jennifer B McClure, Gary E Swan

Abstract readReview
PubMed Publisher
In one paragraph

Review in CNS drugs, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Adherence to and consumption of nicotine replacement therapy and the relationship with abstinence within a smoking cessation trial in primary care.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  3. Association of PolymorphismInternational journal of environmental research and public health · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene and short-term ability to quit smoking in response to nicotine patch.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2009
    Article
  10. Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2009
    Article
  11. Smoking and chronic obstructive pulmonary disease (COPD). Parallel epidemics of the 21 century.International journal of environmental research and public health · 2009
    Review
  12. Update on pharmacologic and nonpharmacologic therapies for smoking cessation.Canadian family physician Medecin de famille canadien · 2008
    Review
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer B McClureGroup Health Cooperative, Center for Health Studies, Seattle, Washington 98101, USA. McClure.J@GHC.org
Gary E Swan

Funding

Treatment of Nicotine Dependence in Health Care SettingR01CA071358 · NCI · SRI INTERNATIONAL · PI SWAN, GARY E · 1997 to 2009
$3.8M
Proactive Cessation Intervention with Biomarker FeedbackR01CA100341 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI MCCLURE, JENNIFER B · 2004 to 2008
$1.5M
NCI NIH HHS 2 R01 CA71358NCI NIH HHS R01 CA100341
6 · The paper itself

Abstract

Nicotine replacement therapy (NRT) is an effective treatment for smoking cessation, but as with all such pharmacotherapies, the majority of smokers who use NRT products do not stop smoking or remain abstinent long term. Treatment outcome is affected by a range of individual-specific factors, as well as the pharmacokinetic profile of each NRT formulation. This has led to speculation that abstinence rates could be improved if NRT treatments were individually tailored to best match each individual's needs and preferences. There are also populations for whom special product and dosage considerations are warranted to maximise treatment safety.This paper reviews the rationale for NRT treatment, standard dose recommendations and recommendations for how to best match NRT treatment to the specific needs of individual smokers. We also review emerging evidence that genetic profiling may one day be a useful consideration for tailoring NRT treatment.

Indexed as

AnimalsDrug Delivery SystemsDrug EruptionsHumansNicotineNicotinic AgonistsSmoking CessationTobacco Use DisorderNicotineNicotinic Agonists

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.