Trial reportClinical research in cardiology : official journal of the German Cardiac Society2006
Implementation of evidence-based therapy in patients with systolic heart failure from 1998-2000.
Trial report in Clinical research in cardiology : official journal of the German Cardiac Society, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Primary ICD-therapy in patients with advanced heart failure: selection strategies and future trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
- Review
- Guideline adherence for pharmacotherapy of chronic systolic heart failure in general practice: a closer look on evidence-based therapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
- The case for statin therapy in chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Review
- Atrial tachycardias following circumferential pulmonary vein ablation: observations during catheter ablation.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
- Long-term prognosis after cardioversion of the first episode of symptomatic atrial fibrillation: a condition believed to be benign revised.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
- Beta blockers and glucose metabolism in chronic heart failure: friend or foe?Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
- Severe cardiomyopathy in a patient with renal cell carcinoma after treatment with the novel tyrosine kinase inhibitor sunitinib.Clinical research in cardiology : official journal of the German Cardiac Society · 2007Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, the incidence of systolic heart failure has increased. Besides a complete revascularization, guideline-based medication represents the most effective therapeutic approach.
aimAnalysis of adherence of guideline-recommended and actual medication during inpatient cardiac rehabilitation as well as under subsequent outpatient conditions.
methodsFrom 01/1998 to 12/ 2000, 1346 consecutive patients (64 +/- 10 years, 73% male, LVEF 36.3 +/- 8%, 88% ischemic, 6.7% valvular cardiomyopathy, 5.3% other causes, 11.8% atrial fibrillation) were included in a singlecenter prospective register. Medication was recorded at discharge and after the follow-up period of 731 +/- 215 days. Trends in prescription rates were analyzed based on nonparametric correlations (Spearman's-Rho). Changes in medication from in- to outpatient settings were analyzed using exact McNemar test.
resultsAt discharge 75.3% (67.9%/68.9%/ 86.6% in 1998/1999/2000, p <0.001) of the patients were treated as recommended. This rate dropped to 68.3% at followup (p <0.0001). Mortality within the follow-up period was low (12.6%).
conclusionIt could be shown that from 1998 to 2000 inpatient guideline conformity was implementable adequately. Outpatient conformity was significantly lower. Although a high proportion of correctly prescribed CHF medication could be demonstrated, a further effort to improve guideline adherence in the management of heart failure patients is desirable.
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