ArticleJournal of clinical microbiology2006
Occurrence of overlooked zoonotic tuberculosis: detection of Mycobacterium bovis in human cerebrospinal fluid.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Association between livestock exposures and human tuberculosis in Wardha, Central India: An exploratory case-control study.PloS one · 2026Article
- Review
- Evaluation of ELISA and PCR in parallel to single intradermal cervical tuberculin test (SICT) for diagnosis of tuberculosis in buffaloes.Tropical animal health and production · 2021Article
- ReconsideringThe Lancet. Microbe · 2020Article
- Culture positivity of smear negative pulmonary and extrapulmonary tuberculosis- A study from North Kerala, India.Journal of family medicine and primary care · 2019Article
- Community, system and policy level drivers of bovine tuberculosis in smallholder periurban dairy farms in India: a qualitative enquiry.BMC public health · 2019Article
- Risk factors for human Mycobacterium bovis infections in an urban area of Brazil.Memorias do Instituto Oswaldo Cruz · 2018Article
- Prevalence of zoonotic tuberculosis and associated risk factors in Central Indian populations.Journal of epidemiology and global health · 2017Article
- Antimycobacterial activity of Pichia pastoris-derived mature bovine neutrophil β-defensins 5.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
- Prevalence of bovine tuberculosis in slaughtered cattle identified by nested-PCR in abattoirs from two dairy areas of Ecuador.Tropical animal health and production · 2014Article
- Detection of IS6110 and HupB gene sequences of Mycobacterium tuberculosis and bovis in the aortic tissue of patients with Takayasu's arteritis.BMC infectious diseases · 2012Article
- Extra pulmonary tuberculosis: a diagnostic dilemma.Indian journal of clinical biochemistry : IJCB · 2011Article
- PCR-Based Evaluation of Tuberculous Endometritis in Infertile Women of North India.Journal of reproduction & infertility · 2011Article
- Article
- Visual format for detection of Mycobacterium tuberculosis and M. bovis in clinical samples using molecular beacons.The Journal of molecular diagnostics : JMD · 2009Article
- Association of tuberculous endometritis with infertility and other gynecological complaints of women in India.Journal of clinical microbiology · 2008Article
- Filtration of cerebrospinal fluid improves isolation of mycobacteria.Journal of clinical microbiology · 2008Article
- Simultaneous detection of Mycobacterium bovis and Mycobacterium tuberculosis in human cerebrospinal fluid.Journal of clinical microbiology · 2007Article
- Diagnostic Challenges and Prospects Associated With Zoonotic Tuberculosis of Central Nervous System.Basic and clinical neuroscienceArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The paucibacillary nature of the cerebrospinal fluid (CSF) has been a major obstacle in the diagnosis of human tuberculous meningitis (TBM). This study shows that with molecular techniques direct precise determination to the species level of mycobacterial pathogens can be made. The present report describes the utility of a nested PCR (N-PCR) assay (A. Mishra, A. Singhal, D. S. Chauhan, V. M. Katoch, K. Srivastava, S. S. Thakral, S. S. Bharadwaj, V. Sreenivas, and H. K. Prasad, J. Clin. Microbiol. 43:5670-5678, 2005) in detecting M. tuberculosis and M. bovis in human CSF. In 2.8% (6/212) of the samples, M. tuberculosis was detected, and in 17% (36/212), M. bovis was detected. Mixed infection was observed in 22 samples. Comparative analysis of clinical diagnosis, smear microscopy, and N-PCR in 69 patients (TBM, 25; non-TBM, 44) showed that the sensitivity of N-PCR (61.5%) was greater than that of smear microscopy (38.4%). Determination to the species level is important from the viewpoint of determining the prevalence of these mycobacteria in a community and would influence strategies currently adopted for the prevention of tuberculosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.