ReviewEMBO reports2006
Psychrophilic microorganisms: challenges for life.
Review in EMBO reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 260 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
260 citing papers in PubMed.
- Microfluidic-based high-throughput isolation enhances the recovery of novel strains and diversity from Arctic soil microbiome.Applied and environmental microbiology · 2026Article
- Assessment of pathogenic traits in selected bacteria isolated from snowy environments in France and Greenland.Extremophiles : life under extreme conditions · 2026Article
- Active layer microbial inocula restore missing functions across thawed permafrost soils.Nature communications · 2026Article
- Hydrothermal regimes regulate microbiome patterns across vertical profile and their responses to alpine permafrost degradation.Nature communications · 2026Article
- Cold-Active Postbiotics from Fermented Food-Derived Lactobacillus fuchuensis H.Y.35 Exhibit Multifunctional In Vitro Bioactivities.Probiotics and antimicrobial proteins · 2026Article
- Evaluating the Potential ofFoods (Basel, Switzerland) · 2026Article
- Structure-Guided Discovery of a Cold-Responsive Antifreeze-like Protein from AntarcticMicroorganisms · 2026Article
- Screening and Efficacy Evaluation of Deodorizing Microbes for Manure Waste in Cold Regions: A Case Study of Xinjiang, China.Microorganisms · 2026Article
- Epigenetic Phase Variation in Bacterial Adaptation to Environmental Stress: A Narrative Review.Current microbiology · 2026Review
- Partial purification and characterization of an extracellular cold-active protease from Flavobacterium azizsancarii, a novel Antarctic isolate.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Metagenomic analysis of bacterial diversity, antibiotic resistance, and functional profiles in the ice core samples from two glaciers of Sikkim Himalaya.Scientific reports · 2026Article
- Crystal structure of a cold-active arginase from Glaciozyma antarctica.Acta crystallographica. Section F, Structural biology communications · 2026Article
- Adaptation of Folding and Function of a Nuclease from the Cold Deep Sea.Journal of molecular biology · 2026Article
- Comprehensive genomic analyses revealed the adaptation strategies ofFrontiers in microbiology · 2026Article
- Antarctic snow algal responses to temperature - potential implications of climate change.Sustainable microbiology · 2026Article
- Genomic and phenotypic characterization of AntarcticFrontiers in microbiology · 2026Article
- Bacterial Diversity of Arctic Soils with Long-Standing Pollution by Petroleum Products and Heavy Metals.Microorganisms · 2025Article
- Integrating natural language processing and genome analysis enables accurate bacterial phenotype prediction.NAR genomics and bioinformatics · 2025Article
- Holobiome Structure and Microbial Core Assemblages ofPlants (Basel, Switzerland) · 2025Article
- Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles.Nature communications · 2025Article
200 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of psychrophiles to survive and proliferate at low temperatures implies that they have overcome key barriers inherent to permanently cold environments. These challenges include: reduced enzyme activity; decreased membrane fluidity; altered transport of nutrients and waste products; decreased rates of transcription, translation and cell division; protein cold-denaturation; inappropriate protein folding; and intracellular ice formation. Cold-adapted organisms have successfully evolved features, genotypic and/or phenotypic, to surmount the negative effects of low temperatures and to enable growth in these extreme environments. In this review, we discuss the current knowledge of these adaptations as gained from extensive biochemical and biophysical studies and also from genomics and proteomics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.