ArticleArchives of virology2006
Molecular analysis of Brazilian strains of bovine coronavirus (BCoV) reveals a deletion within the hypervariable region of the S1 subunit of the spike glycoprotein also found in human coronavirus OC43.
Article in Archives of virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 43 citations in OpenAlex.
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- Molecular detection of coronavirus in camelids and bovines using real-time quantitative polymerase chain reaction in Wasit Province, Iraq.Open veterinary journal · 2025Article
- Detection and molecular characterization of major enteric pathogens in calves in central Ethiopia.BMC veterinary research · 2024Article
- Persistence of two coronaviruses and efficacy of steam vapor disinfection on two types of carpet.Virology journal · 2024Article
- Advances in Laboratory Diagnosis of Coronavirus Infections in Cattle.Pathogens (Basel, Switzerland) · 2024Review
- Characterization and Spike Gene Analysis of a Candidate Attenuated Live Bovine Coronavirus Vaccine.Animals : an open access journal from MDPI · 2024Article
- Development of an IgY-Based Treatment to Control Bovine Coronavirus Diarrhea in Dairy Calves.Viruses · 2023Article
- Advances in Bovine Coronavirus Epidemiology.Viruses · 2022Review
- Bovine coronavirus infections in Turkey: molecular analysis of the full-length spike gene sequences of viruses from digestive and respiratory infections.Archives of virology · 2021Article
- Coronaviruses in farm animals: Epidemiology and public health implications.Veterinary medicine and science · 2021Review
- Bovine coronavirus in neonatal calf diarrhoea in Iran.Veterinary medicine and science · 2020Article
- First report of group A rotavirus and bovine coronavirus associated with neonatal calf diarrhea in the northwest of Argentina.Tropical animal health and production · 2020Article
- Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries.Archives of virology · 2019Article
- Genetic characterization of bovine coronavirus in Vietnam.Virus genes · 2019Article
- Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection.Journal of medical virology · 2017Article
- Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994-2010.Veterinary microbiology · 2015Article
- Antigenic variation among recent Japanese isolates of bovine coronaviruses belonging to phylogenetically distinct genetic groups.Archives of virology · 2013Article
- A multigene approach for comparing genealogy of Betacoronavirus from cattle and horses.TheScientificWorldJournal · 2013Article
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6 authors at 2 institutions in 1 country.
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Abstract
Bovine coronavirus (BCoV) causes enteric and respiratory dis- orders in calves and dysentery in cows. In this study, 51 stool samples of calves from 10 Brazilian dairy farms were analysed by an RT-PCR that amplifies a 488-bp fragment of the hypervariable region of the spike glycoprotein gene. Maximum parsimony genealogy with a heuristic algorithm using sequences from 15 field strains studied here and 10 sequences from GenBank and bredavirus as an outgroup virus showed the existence of two major clusters (1 and 2) in this viral species, the Brazilian strains segregating in both of them. The mean nucleotide identity between the 15 Brazilian strains was 98.34%, with a mean amino acid similarity of 98%. Strains from cluster 2 showed a deletion of 6 amino acids inside domain II of the spike protein that was also found in human coronavirus strain OC43, supporting the recent proposal of a zoonotic spill- over of BCoV. These results contribute to the molecular characterization of BCoV, to the prediction of the efficiency of immunogens, and to the definition of molecular markers useful for epidemiologic surveys on coronavirus-caused diseases.
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