Evidence map›Paper›PMID 16582424›Full record

ArticleGenetics2006

Telomeric silencing of an open reading frame in Saccharomyces cerevisiae.

Arnold B Barton, David B Kaback

Abstract read
In one paragraph

Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins.Proceedings of the National Academy of Sciences of the United States of America · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arnold B BartonDepartment of Microbiology and Molecular Genetics, International Center for Public Health, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103, USA.
David B Kaback

Funding

MOLECULAR STRUCTURE OF YEAST CHROMOSOME IR01GM053924 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KABACK, DAVID B · 1996 to 2005
$786k
NIGMS NIH HHS GM053924NIGMS NIH HHS R01 GM053924
6 · The paper itself

Abstract

The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.

Indexed as

Gene SilencingBase SequenceChromosomes, FungalDNA, FungalGenes, FungalMutationOpen Reading FramesSaccharomyces cerevisiaeSilent Information Regulator Proteins, Saccharomyces cerevisiaeTelomereDNA, FungalSilent Information Regulator Proteins, Saccharomyces cerevisiaeSIR3 protein, S cerevisiae

Identifiers

PMID16582424
PMCPMC1526490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.