ArticleRNA (New York, N.Y.)2006
Transcriptional termination sequences in the mouse serum albumin gene.
Article in RNA (New York, N.Y.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Unraveling 3'-end RNA uridylation at nucleotide resolution.Methods (San Diego, Calif.) · 2019Review
- Characterization of a novel antisense RNA in the major pilin locus of Neisseria meningitidis influencing antigenic variation.Journal of bacteriology · 2015Article
- Article
- A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters.PloS one · 2012Article
- A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination.Nucleic acids research · 2010Article
- Article
- Transcription termination by nuclear RNA polymerases.Genes & development · 2009Article
- Transcriptional termination enhances protein expression in human cells.Molecular cell · 2009Article
- A manganese-dependent ribozyme in the 3'-untranslated region of Xenopus Vg1 mRNA.Nucleic acids research · 2008Article
- A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3' end RNA polyadenylation.Genome research · 2008Article
- Molecular dissection of mammalian RNA polymerase II transcriptional termination.Molecular cell · 2008Article
- Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.Nucleic acids research · 2008Article
- The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity.RNA (New York, N.Y.) · 2006Article
- Pause sites promote transcriptional termination of mammalian RNA polymerase II.Molecular and cellular biology · 2006Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Poly(A) signals are required for efficient 3' end formation and transcriptional termination of most protein-encoding genes transcribed by RNA polymerase II. However, transcription can extend far beyond the poly(A) site before termination occurs. This implies the existence of further downstream termination signals. In mammals, a variety of sequence elements, in addition to the poly(A) site, have been implicated in the termination process. For example, termination of the human beta- and epsilon-globin genes is mediated by a sequence downstream of the poly(A) site that promotes an RNA cotranscriptional cleavage (CoTC). Here we report the identification of multiple termination sequences in the mouse serum albumin (MSA) 3' flanking region. Many transcripts from this region are cleaved cotranscriptionally, implying that such cleavage of pre-mRNA may be a more general feature of transcriptional termination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.