Evidence map›Paper›PMID 16581558›Full record

ReviewEnvironmental health perspectives2006

A brief targeted review of susceptibility factors, environmental exposures, asthma incidence, and recommendations for future asthma incidence research.

Karin Yeatts, Peter Sly, Stephanie Shore, Scott Weiss, Fernando Martinez, Andrew Geller, Philip Bromberg, Paul Enright, Hillel Koren, David Weissman and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pediatric asthma incidence rates in the United States from 1980 to 2017.The Journal of allergy and clinical immunology · 2021
    Article
  5. Article
  6. Article
  7. Children's Inter-Individual Variability and Asthma Development.International journal of health sciences · 2015
    Review
  8. Ensuring healthy American Indian generations for tomorrow through safe and healthy indoor environments.International journal of environmental research and public health · 2015
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. An understanding of the genetic basis of asthma.The Indian journal of medical research · 2011
    Review
  14. Regulating the Regulators: microRNA and Asthma.The World Allergy Organization journal · 2011
    Article
  15. Biomarkers of immunotoxicity for environmental and public health research.International journal of environmental research and public health · 2011
    Review
  16. Systemic inflammation and reduced pulmonary function in chronic spinal cord injury.PM & R : the journal of injury, function, and rehabilitation · 2011
    Article
  17. Article
  18. Review
  19. Article
  20. Cancer risk in hospitalised asthma patients.British journal of cancer · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Karin YeattsCenter for Environmental Medicine, Asthma, and Lung Biology, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599, USA. Karin_Yeatts@unc.edu
Peter Sly
Stephanie Shore
Scott Weiss
Fernando Martinez
Andrew Geller
Philip Bromberg
Paul Enright
Hillel Koren
David Weissman
MaryJane Selgrade
Environmental Protection Agency · USHarvard University · USUniversity of Arizona · USUniversity of North Carolina at Chapel Hill · USNational Institute for Occupational Safety and Health · USThe University of Western Australia · AU

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$44.6M
Natural History of Asthma from Birth to Early Adult LifeR01HL056177 · NHLBI · UNIVERSITY OF ARIZONA · PI GUERRA, STEFANO, MARTINEZ, FERNANDO D · 1996 to 2015
$14.4M
RESISTANCE OF THE CELL TO SHAPE DISTORTION--BASIS OF CYTOSKELETAL MECHANICSP01HL033009 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI FREDBERG, JEFFREY J · 1985 to 2005
$10.0M
SNPs in transcriptional regulation of CD14P50HL067672 · NHLBI · UNIVERSITY OF ARIZONA · PI KLIMECKI, WALTER T. · 2002 to 2005
$5.0M
CHROMOSOME 5Q GENE VARIANTS AND ASTHMA-RELATED TRAITSR01HL066447 · NHLBI · UNIVERSITY OF ARIZONA · PI MARTINEZ, FERNANDO D · 2000 to 2004
$2.5M
ENDOTOXIN AND BRONCHIAL INFLAMMATION IN ASTHMAR01HL062624 · NHLBI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B · 1999 to 2005
$1.6M
SNPs in transcriptional regulation of CD14P01HL067672 · NHLBI · UNIVERSITY OF ARIZONA · PI HALONEN, MARILYN J · 2001 to 2001
$1.4M
NHLBI NIH HHS HL 33009NHLBI NIH HHS HL 56177NHLBI NIH HHS HL 66447NHLBI NIH HHS HL 67672NHLBI NIH HHS P01 HL033009NHLBI NIH HHS P01 HL067672NHLBI NIH HHS P50 HL067672NHLBI NIH HHS R01 HL056177NHLBI NIH HHS R01 HL062624NHLBI NIH HHS R01 HL066447NHLBI NIH HHS R01 HL 62624NIEHS NIH HHS ES 00002NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

Relative to research on effects of environmental exposures on exacerbation of existing asthma, little research on incident asthma and environmental exposures has been conducted. However, this research is needed to better devise strategies for the prevention of asthma. The U.S. Environmental Protection Agency (EPA) and National Institute of Environmental Health Sciences held a conference in October 2004 to collaboratively discuss a future research agenda in this area. The first three articles in this mini-monograph summarize the discussion on potential putative environmental exposure; they include an overview of asthma and conclusions of the workshop participants with respect to public health actions that could currently be applied to the problem and research needs to better understand and control the induction and incidence of asthma, the potential role of indoor/outdoor air pollutants in the induction of asthma), and biologics in the induction of asthma. Susceptibility is a key concept in the U.S. EPA "Asthma Research Strategy" document and is associated with the U.S. EPA framework of protecting vulnerable populations from potentially harmful environmental exposures. Genetics, age, and lifestyle (obesity, diet) are major susceptibility factors in the induction of asthma and can interact with environmental exposures either synergistically or antagonistically. Therefore, in this fourth and last article we consider a number of "susceptibility factors" that potentially influence the asthmatic response to environmental exposures and propose a framework for developing research hypotheses regarding the effects of environmental exposures on asthma incidence and induction.

Indexed as

Disease SusceptibilityEnvironmental ExposureAsthmaHumansHygieneIncidenceLife StyleObesityOccupational Diseases

Identifiers

PMID16581558
PMCPMC1440793
OpenAlexW2152705977

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.