ArticleEnvironmental health perspectives2006
Airborne endotoxin is associated with respiratory illness in the first 2 years of life.
Article in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 72 citations in OpenAlex.
- Influence of exposure to coarse, fine and ultrafine urban particulate matter and their biological constituents on neural biomarkers in a randomized controlled crossover study.Environment international · 2017Trial
- Effects of ambient coarse, fine, and ultrafine particles and their biological constituents on systemic biomarkers: a controlled human exposure study.Environmental health perspectives · 2015Trial
- Article
- Housing conditions and respiratory morbidity in Indigenous children in remote communities in Northwestern Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Birth cohort studies using symptom diaries for assessing respiratory diseases-a scoping review.PloS one · 2022Article
- Household airborne endotoxin associated with asthma and allergy in elementary school-age children: a case-control study in Kaohsiung, Taiwan.Environmental science and pollution research international · 2020Article
- Predictors and respiratory depositions of airborne endotoxin in homes using biomass fuels and LPG gas for cooking.Journal of exposure science & environmental epidemiology · 2017Article
- Urban Enhancement of PMJournal of geophysical research. Atmospheres : JGR · 2016Article
- Contribution of solid fuel, gas combustion, or tobacco smoke to indoor air pollutant concentrations in Irish and Scottish homes.Indoor air · 2012Article
- Use of a robotic sampling platform to assess young children's exposure to indoor bioaerosols.Indoor air · 2012Article
- Respiratory and allergic health effects of dampness, mold, and dampness-related agents: a review of the epidemiologic evidence.Environmental health perspectives · 2011Review
- Predictors of airborne endotoxin concentrations in inner city homes.Environmental research · 2011Article
- Exposure assessment in Beijing, China: biological agents, ultrafine particles, and lead.Environmental monitoring and assessment · 2010Article
- Visually observed mold and moldy odor versus quantitatively measured microbial exposure in homes.The Science of the total environment · 2010Article
- Temporal and spatial patterns of ambient endotoxin concentrations in Fresno, California.Environmental health perspectives · 2010Article
- Do questions reflecting indoor air pollutant exposure from a questionnaire predict direct measure of exposure in owner-occupied houses?International journal of environmental research and public health · 2010Article
- Airborne endotoxin concentrations in homes burning biomass fuel.Environmental health perspectives · 2010Article
- Role of infections in the induction and development of asthma: genetic and inflammatory drivers.Expert review of clinical immunology · 2009Article
- Quality of indoor residential air and health.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2008Review
- Indoor and outdoor particulate matter and endotoxin concentrations in an intensely agricultural county.Journal of exposure science & environmental epidemiologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine the influence of endotoxin on the incidence of acute respiratory illness during the first 2 years of life, we carried out a longitudinal follow-up study, beginning at birth, of 332 children born in Prince Edward Island, Canada. We measured 5-day averaged air endotoxin in the homes of children, whose parents provided information by daily symptom diaries and twice-monthly telephone contact for up to 2 years. Endotoxin concentration was 0.49 +/- 3.49 EU/m3 (geometric mean +/- geometric SD), and number of annualized illness episodes was 6.83 +/- 2.80 (mean +/- SD). A doubling of the air endotoxin concentration was associated with an increase of 0.32 illness episodes per year (p = 0.0003), adjusted for age, year of study, breast-feeding, environmental tobacco smoke, child care attendance, indoor temperature, and income. Indoor mold surface area and fungal ergosterol were not significantly associated with endotoxin. Airborne endotoxin appears to be a risk factor for clinically symptomatic respiratory illnesses during the first 2 years of life independent of indoor fungus.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.